An ionic liquid influenced L-proline catalysed asymmetric Michael addition of ketones to nitrostyrene

被引：114

作者：

Rasalkar, MS ^{[1
]}

Potdar, MK ^{[1
]}

Mohile, SS ^{[1
]}

Salunkhe, MM ^{[1
]}

机构：

[1] Inst Sci, Dept Chem, Bombay 400032, Maharashtra, India

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2005年 / 235卷 / 1-2期

关键词：

L-proline; ionic liquids Michael addition; enantioselectivity; recyclability;

D O I：

10.1016/j.molcata.2005.03.024

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

L-Proline in ionic liquid was employed for Michael addition of ketones to nitrostyrene. Optically active gamma-nitroketones were obtained in good yields up to 80%. The reaction offers high syn selectivity (90%). The most striking feature is that the ionic liquid has been found to enhance the enantioselectivity, wherein enantiomeric excess approaches 75%. The system of ionic liquid and catalyst has proved to be an efficient recyclable medium. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：267 / 270

页数：4

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