Tackling antibiotic resistance: the environmental framework

被引：1783

作者：

Berendonk, Thomas U. ^{[1
]}

Manaia, Celia M. ^{[2
]}

Merlin, Christophe ^{[3
,4
]}

Fatta-Kassinos, Despo ^{[5
,6
]}

Cytryn, Eddie ^{[7
]}

Walsh, Fiona ^{[8
]}

Buergmann, Helmut ^{[9
]}

Sorum, Henning ^{[10
]}

Norstrom, Madelaine ^{[11
]}

Pons, Marie-Noelle ^{[12
]}

Kreuzinger, Norbert ^{[13
]}

Huovinen, Pentti ^{[14
]}

Stefani, Stefania ^{[15
]}

Schwartz, Thomas ^{[16
]}

Kisand, Veljo ^{[17
]}

Baquero, Fernando ^{[18
]}

Luis Martinez, Jose ^{[19
]}

机构：

[1] Tech Univ Dresden, Inst Hydrobiol, D-01062 Dresden, Germany

[2] Univ Catolica Portuguesa Porto, Escola Super Biotecnol, Lab Associado, Ctr Biotecnol & Quim Fina, P-4202401 Porto, Portugal

[3] Univ Lorraine, F-54500 Vandoeuvre Les Nancy, France

[4] CNRS, Unite Mixte Rech 7564, Lab Chim Phys & Microbiol Environm, F-54500 Vandoeuvre Les Nancy, France

[5] Univ Cyprus, Int Water Res Ctr, Civil & Environm Engn Dept, CY-1678 Nicosia, Cyprus

[6] Univ Cyprus, Int Water Res Ctr, Nireas, CY-1678 Nicosia, Cyprus

[7] Agr Res Org, Inst Soil Water & Environm Sci, Volcani Ctr, IL-50250 Bet Dagan, Israel

[8] Natl Univ Ireland Maynooth, Dept Biol, Maynooth, Kildare, Ireland

[9] Swiss Fed Inst Aquat Sci & Technol, Dept Surface Waters Res & Management, CH-6047 Kastanienbaum, Switzerland

[10] Norwegian Univ Life Sci, Fac Vet Med & Life Sci, Dept Food Safety & Infect Biol, N-0033 Oslo, Norway

[11] Norwegian Vet Inst, Dept Epidemiol, N-0106 Oslo, Norway

[12] Univ Lorraine, Lab React & Genie Proc, UMR CNRS 7274, F-54000 Nancy, France

[13] Vienna Univ Technol, Inst Water Qual Resources & Waste Management, A-1040 Vienna, Austria

[14] Univ Turku, Dept Med Microbiol & Immunol, FIN-20520 Turku, Finland

[15] Univ Catania, Dept Biomed Sci, Lab Mol Microbiol & Antibiot Resistance, I-95124 Catania, Italy

[16] Karlsruhe Inst Technol, Inst Funct Interfaces, Microbiol Nat & Tech Interfaces Dept, D-76344 Eggenstein Leopoldshafen, Germany

[17] Univ Tartu, Inst Technol, EE-50411 Tartu, Estonia

[18] Ramon & Cajal Univ Hosp, Ramon & Cajal Inst Hlth Res, Dept Microbiol, Madrid 28034, Spain

[19] Consejo Super Invest, Ctr Nacl Biotecnol, Dept Biotecnol, Madrid 28049, Spain

来源：

NATURE REVIEWS MICROBIOLOGY | 2015年 / 13卷 / 05期

关键词：

WASTE-WATER TREATMENT; ANTIMICROBIAL RESISTANCE; SELECTIVE PRESSURE; TREATMENT PLANTS; GENE-EXPRESSION; BACTERIA; SOIL; EVOLUTION; PREVALENCE; MANURE;

D O I：

10.1038/nrmicro3439

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学];

摘要：

Antibiotic resistance is a threat to human and animal health worldwide, and key measures are required to reduce the risks posed by antibiotic resistance genes that occur in the environment. These measures include the identification of critical points of control, the development of reliable surveillance and risk assessment procedures, and the implementation of technological solutions that can prevent environmental contamination with antibiotic resistant bacteria and genes. In this Opinion article, we discuss the main knowledge gaps, the future research needs and the policy and management options that should be prioritized to tackle antibiotic resistance in the environment.

引用

页码：310 / 317

页数：8

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