Lymphadenectomy in Urologic Oncology: Pathologic Considerations

被引:4
作者
Alexander, Riley E. [1 ]
Sung, Ming-Tse [2 ,3 ,4 ]
Cheng, Liang [1 ,5 ]
机构
[1] Indiana Univ Sch Med, Dept Pathol & Lab Med, Indianapolis, IN 46202 USA
[2] Kaohsiung Chang Gung Mem Hosp, Dept Pathol, Kaohsiung 833, Taiwan
[3] Chang Gung Univ, Coll Med, Kaohsiung 833, Taiwan
[4] Kaohsiung Chang Gung Mem Hosp, Dept Lab Med, Kaohsiung 833, Taiwan
[5] Indiana Univ Sch Med, Dept Urol, Indianapolis, IN 46202 USA
关键词
Lymphadenectomy; Urothelial cancer; Urinary bladder; Staging and classification; Sampling and reporting; LYMPH-NODE DISSECTION; PROSTATE-SPECIFIC ANTIGEN; RENAL-CELL CARCINOMA; INVASIVE BLADDER-CANCER; DISEASE-FREE SURVIVAL; UPPER URINARY-TRACT; RADICAL PROSTATECTOMY; UROTHELIAL CARCINOMA; PELVIC LYMPHADENECTOMY; EXTRACAPSULAR EXTENSION;
D O I
10.1016/j.ucl.2011.07.001
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
100201 [内科学]; 100221 [泌尿外科学];
摘要
Lymphadenectomy (LAD) is an important staging and treatment modality of oncologic surgery. LAD in genitourinary malignancies presents inherent difficulties to the urologist and pathologist because of the differences in anatomic sites and primary histologic type. This review focuses on pathologic evaluation and how communication between urologist and pathologist is necessary to provide optimal care. Recommendations covering general specimen submission and processing are discussed, as well as more specific recommendations concerning the kidney, upper urinary tract, urinary bladder, prostate, testes, and penis. Emerging areas of prognostic significance and the impact that improved molecular techniques are contributing to diagnostic interpretation are highlighted.
引用
收藏
页码:483 / +
页数:14
相关论文
共 81 条
[1]
Intraoperative frozen section diagnosis in urological oncology [J].
Algaba, F ;
Arce, Y ;
López-Beltrán, A ;
Montironi, R ;
Mikuz, G ;
Bono, A .
EUROPEAN UROLOGY, 2005, 47 (02) :129-136
[2]
Handling and pathology reporting of renal tumor specimens [J].
Algaba, F ;
Trias, I ;
Scarpelli, M ;
Boccon-Gibod, L ;
Kirkali, Z ;
Van Poppel, H .
EUROPEAN UROLOGY, 2004, 45 (04) :437-443
[3]
Multifocal prostate cancer: biologic, prognostic, and therapeutic implications [J].
Andreoiu, Matei ;
Cheng, Liang .
HUMAN PATHOLOGY, 2010, 41 (06) :781-793
[4]
Does the histology of nodal metastasis predict systemic relapse after retroperitoneal lymph node dissection in pathological stage B1 germ cell tumors? [J].
Beck, SDW ;
Foster, RS ;
Bihrle, R ;
Cheng, L ;
Donohue, JP .
JOURNAL OF UROLOGY, 2005, 174 (04) :1287-1290
[5]
Impact of the number of positive lymph nodes on disease-free survival in patients with pathological stage B1 nonseminomatous germ cell tumor [J].
Beck, SDW ;
Foster, RS ;
Bihrle, R ;
Cheng, L ;
Ulbright, TM ;
Donohue, JP .
JOURNAL OF UROLOGY, 2005, 174 (01) :143-145
[6]
Does the presence of extranodal extension in pathological stage B1 nonseminomatous germ cell tumor necessitate adjuvant chemotherapy? [J].
Beck, Stephen D. W. ;
Cheng, Liang ;
Bihrle, Richard ;
Donohue, John P. ;
Foster, Richard S. .
JOURNAL OF UROLOGY, 2007, 177 (03) :944-946
[7]
BERNEY DM, 2010, MODERN PATHOL, V24, P39
[8]
Radical Nephrectomy with and without Lymph-Node Dissection: Final Results of European Organization for Research and Treatment of Cancer (EORTC) Randomized Phase 3 Trial 30881 [J].
Blom, Jan H. M. ;
van Poppel, Hein ;
Marechal, Jean M. ;
Jacqmin, Didier ;
Schroder, Fritz H. ;
de Prijck, Linda ;
Sylvester, Richard .
EUROPEAN UROLOGY, 2009, 55 (01) :28-34
[9]
ELIMINATING THE NEED FOR BILATERAL PELVIC LYMPHADENECTOMY IN SELECT PATIENTS WITH PROSTATE-CANCER [J].
BLUESTEIN, DL ;
BOSTWICK, DG ;
BERGSTRALH, EJ ;
OESTERLING, JE .
JOURNAL OF UROLOGY, 1994, 151 (05) :1315-1320
[10]
Handling and pathology reporting of prostate biopsies [J].
Boccon-Gibod, L ;
van der Kwast, TH ;
Montironi, R ;
Boccon-Gibod, L ;
Bono, A .
EUROPEAN UROLOGY, 2004, 46 (02) :177-181