Simple iron catalyst for terminal alkene epoxidation

被引：127

作者：

Dubois, G ^{[1
]}

Murphy, A ^{[1
]}

Stack, TDP ^{[1
]}

机构：

[1] Stanford Univ, Dept Chem, Stanford, CA 94305 USA

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 14期

关键词：

D O I：

10.1021/ol0347085

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

graphic A mu-oxo-iron(III) dimer, [((phen)(2)(H2O)Fe-III)(2)(mu-O)](ClO4)(4), is an efficient epoxidation catalyst for a wide range of alkenes, including terminal alkenes, using peracetic acid as the oxidant. Low catalyst loadings, in situ catalyst preparation from common reagents, fast reaction times (<5 min at 0 degreesC), and enhanced reaction performance at high substrate concentrations combine to create a temporally and synthetically efficient procedure for alkene epoxidation.

引用

页码：2469 / 2472

页数：4

共 27 条

[21] A practical method for epoxidation of terminal olefins with 30% hydrogen peroxide under halide-free conditions [J].