ETV6 gene rearrangements in invasive breast carcinoma

被引：23

作者：

Letessier, A

Ginestier, C

Charafe-Jauffret, E

Cervera, N

Adélaïde, J

Gelsi-Boyer, V

Ahomadegbe, JC

Benard, J

Jacquemier, J

Birnbaum, D

Chaffanet, M

机构：

[1] Inst J Paoli I Calmettes, Marseille Canc Inst, Mol Oncol Lab, INSERM,UMR 599, F-13273 Marseille, France

[2] Inst J Paoli I Calmettes, Dept BioPathol, F-13009 Marseille, France

[3] Univ Mediterranee, UFR Med, Marseille, France

[4] Inst Gustave Roussy, UPRES 3535, Villejuif, France

来源：

GENES CHROMOSOMES & CANCER | 2005年 / 44卷 / 01期

关键词：

D O I：

10.1002/gcc.20200

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The ETV6/TEL gene encodes a transcription factor frequently rearranged in several types of cancer. We looked for ETV6 rearrangements in invasive breast cancer using fluorescence in situ hybridization (FISH) of BAC probes on sections of tissue microarrays containing 632 tumor samples. Of these samples, signal of sufficient quality for screening by FISH was obtained for 356. Five cases (one lobular, one nontypical secretory, one mixed, and two ductal carcinomas) showed ETV6 rearrangement. (c) 2005 Wiley-Liss, Inc.

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页码：103 / 108

页数：6

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