Prevalence of hepatitis-B surface antigen among blood donors and human immunodeficiency virus-infected patients in Jos, Nigeria

被引：67

作者：

Uneke, CJ

Ogbu, O

Inyama, PU

Anyanwu, GI

Njoku, MO

Idoko, JH

机构：

[1] Ebonyi State Univ, Dept Med Microbiol, Fac Clin Med, Coll Hlth Sci, Abakaliki, Nigeria

[2] Univ Jos, AIDS Leishmaniasis Res Lab, Dept Zool, Jos, Nigeria

[3] GEDE AIDS & Infect Dis Res Inst, Maitama Abuja, Nigeria

[4] Univ Jos, Teaching Hosp, Dept Med Microbiol, Jos, Nigeria

来源：

MEMORIAS DO INSTITUTO OSWALDO CRUZ | 2005年 / 100卷 / 01期

关键词：

hepatitis B virus; human immunodeficiency virus; blood donor; prevalence;

D O I：

10.1590/S0074-02762005000100002

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Information is very scarce on the prevalence of hepatitis-B virus (HBV) infection among blood donors and patients with human immunodeficiency virus (HIV) infection in Nigeria. Hepatitis-B surface antigen (HBsAg) ELISA was used to determined the prevalence of HBsAg among 175 blood donors (aged 20-40 years) and 490 HIV-infected patients (aged 17 - 60 years) in Jos, Nigeria. Twenty-five (14.3%) of the blood donors and 127 (25.9%) of the HIV-infected individuals were HBsAg seropositive, indicating a higher HBV infection among HIV-infected persons than among healthy blood donors. A slightly higher HBsAg seroprevalence was recorded in the males (14.6%) than females (12.9%) of the blood donors. Among the HIV-infected patients, the males had considerably higher HBsAg seroprevalence than the females (31.8 vs 22.1%) with the highest prevalence of HBsAg occurring in the 51-60 years age group (44%), followed by those of 31-40 years (28.2%). Results confirmed the high endemicity of HBV infection in Jos, Nigeria and the significantly greater prevalence of HBV infection among HIV-infected patients than among blood donors.

引用

页码：13 / 16

页数：4