Glutathione peroxidase-like activities of oxygen-containing diselenides

被引：102

作者：

Wirth, T ^{[1
]}

机构：

[1] Univ Basel, Inst Organ Chem, CH-4056 Basel, Switzerland

来源：

MOLECULES | 1998年 / 3卷 / 07期

关键词：

antioxidants; diselenides; glutathione oxidase; glutathione peroxidase; oxidative stress;

D O I：

10.3390/30700164

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Various diselenides 1-8 have been examined with respect to their glutathione peroxidase-like activities (GPx-activities) as an index of their antioxidant properties. The glutathione oxidase activities of these compounds have also been reviewed reflecting the pro-oxidant properties (GOx-activities) and could be used as an index of cell toxicity.:Based on a qualitative structure-activity relationship some trends are suggested.

引用

页码：164 / 166

页数：3

共 24 条

[1]

[Anonymous], 1986, CHEM ORGANIC SELENIU

[2]

Aumann KD, 1997, BIOMED ENVIRON SCI, V10, P136

[3] A novel camphor-derived selenenamide that acts as a glutathione peroxidase mimetic [J].