Enantioselective synthesis of planar-chiral metacyclophanes through cationic Rh(I)/modified-BINAP-catalyzed inter- and intramolecular alkyne cyclotrimerizations

被引：37

作者：

Tanaka, Ken ^{[1
]}

Sagae, Hirorni ^{[1
]}

Toyoda, Kazuki ^{[1
]}

Hirano, Masao ^{[1
]}

机构：

[1] Tokyo Univ Agr & Technol, Grad Sch Engn, Dept Appl Chem, Koganei, Tokyo 1848588, Japan

来源：

TETRAHEDRON | 2008年 / 64卷 / 05期

关键词：

alkyne; BINAP; cyclotrimerization; metacyclophanes; rhodium;

D O I：

10.1016/j.tet.2007.10.085

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We have achieved the first catalytic enantioselective synthesis of planar-chiral metacyclophanes by means of cationic Rh(I)/(S)-xyl-H-8-BINAP or (R)-H-8-BINAP complex-catalyzed inter- and intramolecular alkyne cyclotrimerizations. This highly enantioselective catalysis represents a versatile new method for the preparation of planar-chiral metacyclophanes. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：831 / 846

页数：16

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