Cobalt-mediated cyclotrimerisation of bis-alkynes and cyanamides

被引:67
作者
Boñaga, LVR [1 ]
Zhang, HC [1 ]
Maryanoff, BE [1 ]
机构
[1] Johnson & Johnson Pharmaceut Res & Dev, Drug Discovery, Spring House, PA 19477 USA
关键词
D O I
10.1039/b410012c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
CpCo(CO)(2)-mediated cyclotrimerisation of bis-alkynes and cyanamides provides multisubstituted 2-aminopyridines, including macrocyclic products, such as 22 (50% yield).
引用
收藏
页码:2394 / 2395
页数:2
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