Measurement of the axial point spread function in scattering media using single-mode fiber-based optical coherence tomography

被引:141
作者
van Leeuwen, TG [1 ]
Faber, DJ
Aalders, MC
机构
[1] Univ Amsterdam, Acad Med Ctr, Ctr Laser, NL-1105 AZ Amsterdam, Netherlands
[2] Univ Twente, Dept Biophys Engn, Biomed Opt Grp, Twente, Netherlands
关键词
optical coherence tomography; point spread function (PSF); tissue optical properties;
D O I
10.1109/JSTQE.2003.813299
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 [电气工程]; 0809 [电子科学与技术];
摘要
The authors studied the axial point spread function of optical coherence tomography for Gaussian intensity profiles emitted from and coupled back into single-mode fibers for signals from a scattering medium. The determined Rayleigh length of the axial point spread function was roughly twice the one measured from the reflection of a mirror. Using the measured point spread function in combination with the single backscatter model allowed determination of the attenuation coefficient of the suspension.
引用
收藏
页码:227 / 233
页数:7
相关论文
共 26 条
[1]
Comparative optical coherence tomography imaging of human esophagus:: How accurate is localization of the muscularis mucosae? [J].
Çilesiz, I ;
Fockens, P ;
Kerindongo, R ;
Faber, D ;
Tytgat, G ;
ten Kate, F ;
van Leeuwen, T .
GASTROINTESTINAL ENDOSCOPY, 2002, 56 (06) :852-857
[2]
Axial resolution of confocal Raman microscopes: Gaussian beam theory and practice [J].
De Grauw, CJ ;
Sijtsema, NM ;
Otto, C ;
Greve, J .
JOURNAL OF MICROSCOPY, 1997, 188 :273-279
[3]
Two-dimensional birefringence imaging in biological tissue by polarization-sensitive optical coherence tomography [J].
deBoer, JF ;
Milner, TE ;
vanGemert, MJC ;
Nelson, JS .
OPTICS LETTERS, 1997, 22 (12) :934-936
[4]
In vivo ultrahigh-resolution optical coherence tomography [J].
Drexler, W ;
Morgner, U ;
Kärtner, FX ;
Pitris, C ;
Boppart, SA ;
Li, XD ;
Ippen, EP ;
Fujimoto, JG .
OPTICS LETTERS, 1999, 24 (17) :1221-1223
[5]
Drexler W, 2001, INVEST OPHTH VIS SCI, V42, pS118
[6]
OPTICAL BIOPSY AND IMAGING USING OPTICAL COHERENCE TOMOGRAPHY [J].
FUJIMOTO, JG ;
BREZINSKI, ME ;
TEARNEY, GJ ;
BOPPART, SA ;
BOUMA, B ;
HEE, MR ;
SOUTHERN, JF ;
SWANSON, EA .
NATURE MEDICINE, 1995, 1 (09) :970-972
[7]
IMAGE-FORMATION IN A FIBEROPTIC CONFOCAL SCANNING MICROSCOPE [J].
GU, M ;
SHEPPARD, CJR ;
GAN, X .
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 1991, 8 (11) :1755-1761
[8]
HITZENBERGER CK, 1991, INVEST OPHTH VIS SCI, V32, P616
[9]
INTERFEROMETRIC MEASUREMENT OF CORNEAL THICKNESS WITH MICROMETER PRECISION [J].
HITZENBERGER, CK ;
BAUMGARTNER, A ;
DREXLER, W ;
FERCHER, AF .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 1994, 118 (04) :468-476
[10]
OPTICAL COHERENCE MICROSCOPY IN SCATTERING MEDIA [J].
IZATT, JA ;
HEE, MR ;
OWEN, GM ;
SWANSON, EA ;
FUJIMOTO, JG .
OPTICS LETTERS, 1994, 19 (08) :590-592