Targeting the central nervous system inflammatory response in ischemic stroke

被引:71
作者
Becker, KJ [1 ]
机构
[1] Univ Washington, Harborview Med Ctr, Sch Med, Dept Neurol, Seattle, WA 98104 USA
关键词
D O I
10.1097/00019052-200106000-00014
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
In experimental models of stroke, inflammation appears to contribute to cerebral ischemic injury. Clinical trials that are aimed at limiting the postischemic inflammatory response, however, have thus far had disappointing results. These clinical failures probably reflect the fact that there has been insufficient preclinical data and inadequate trial design, rather than provide evidence against a role for inflammation in ischemic brain injury. Curr Opin Neurol 14:349-353. (C) 2001 Lippincott Williams & Wilkins.
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收藏
页码:349 / 353
页数:5
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