Copper(II)-catalyzed exo and enantioselective cycloadditions of azomethine imines

被引：110

作者：

Sibi, Mukund P. ^{[1
]}

Rane, Digamber ^{[1
]}

Stanley, Levi M. ^{[1
]}

Soeta, Takahiro ^{[1
]}

机构：

[1] N Dakota State Univ, Dept Chem, Fargo, ND 58105 USA

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 14期

关键词：

D O I：

10.1021/ol800904t

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A strategy for exo and enantioselective 1,3-dipolar cycloaddition of azomethine imines to 2-acryloyl-3-pyrazolidinone is described. The corresponding cycloadducts are isolated with high diastereoselectivities (up to >96:4 exo/endo) and enantioselectivities (up to 98% ee).

引用

页码：2971 / 2974

页数：4

共 26 条

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