Xanthones from Garcinia smeathmannii (Oliver) and their antimicrobial activity

被引：48

作者：

Komguem, J

Meli, AL

Manfouo, RN

Lontsi, D

Ngounou, FN

Kuete, V

Kamdem, HW

Tane, P

Ngadjui, BT

Sondengam, BL

Connolly, JD

机构：

[1] Univ Yaounde, Fac Sci, Dept Organ Chem, Yaounde, Cameroon

[2] Univ Yaounde, Fac Sci, Dept Biochem, Yaounde, Cameroon

[3] Univ Dschang, Fac Sci, Dept Chem, Dschang, Cameroon

[4] Univ Glasgow, Dept Chem, Glasgow G12 8QQ, Lanark, Scotland

来源：

PHYTOCHEMISTRY | 2005年 / 66卷 / 14期

关键词：

Garcinia smeathmannil; Guttiferae; stem bark; xanthone; smeathxanthones A and B; antimicrobial activity;

D O I：

10.1016/j.phytochem.2005.03.010

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Two new xanthones, smeathxanthone A (1) (2-(3,7-dimethyl-2,6-octadienyl)-1,3,5,8-tetrahydroxyxanthone) and smeathxanthone B (2) (5,7,10-trihydroxy-2-methyl-2-(4-methylpent-3-enyl)[2H, 6H]pyrano[3,2-b]xanthen-6-one), have been isolated from the stem bark of Garcinia smeathmannii, and their structures elucidated on the basis of 1D and 2D NMR experiments. 1,3,5-Trihydroxyxanthone and 1,5-dihydroxyxanthone were also obtained. The compounds showed only modest activity against a range of bacteria and yeasts. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：1713 / 1717

页数：5

共 10 条

[1]

XANTHONES FROM 3 GARCINIA SPECIES [J].