Studies toward the total synthesis of GKK1032A2, a structurally unique antitumor compound: Stereoselective construction of the tricarbocyclic system

被引：23

作者：

Arai, N

Ui, H

Omura, S

Kuwajima, I

机构：

[1] Japan Sci & Technol Agcy, CREST, Creat & Funct New Mol & Mol Assemblies, Sagamihara, Kanagawa 2288555, Japan

[2] Kitasato Univ, Sch Pharmaceut Sci, Minato Ku, Tokyo 1088641, Japan

[3] Kitasato Inst, Minato Ku, Tokyo 1088642, Japan

来源：

SYNLETT | 2005年 / 11期

关键词：

antitumor agents; carbocycles; Diels-Alder reactions; natural products; stereoselective synthesis;

D O I：

10.1055/s-2005-871549

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

The unique tricarbocyclic system in GKKI032A(2), an antitumor agent from Penicillium sp. GKK1032, was constructed in a highly stereoselective manner, starting from a readily available Hajos-Wiechert ketone analog.

引用

页码：1691 / 1694

页数：4

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