T cell death and memory

被引：165

作者：

Sprent, J ^{[1
]}

Tough, DF ^{[1
]}

机构：

[1] Scripps Res Inst, Dept Immunol, La Jolla, CA 92037 USA

来源：

SCIENCE | 2001年 / 293卷 / 5528期

关键词：

D O I：

10.1126/science.1062416

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In typical immune responses, contact with antigen causes naive T cells to proliferate and differentiate into effector cells. After the pathogen is destroyed, most effector T cells are eliminated-thereby preserving the primary T cell repertoire-but some cells survive and form long-lived memory cells. During each stage of this process, the Life or death fate of T cells is strictly regulated.

引用

页码：245 / 248

页数：4

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