Fetal sex and maternal asthma control in pregnancy

被引：32

作者：

Bakhireva, Ludmila N. ^{[1
,2
]}

Schatz, Michael ^{[3
]}

Jones, Kenneth Lyons ^{[4
]}

Tucker, Carey M. ^{[5
]}

Slymen, Donald J. ^{[6
]}

Klonoff-Cohen, Hillary S. ^{[7
]}

Gresham, Louise ^{[6
]}

Johnson, Diana ^{[4
]}

Chambers, Christina D. ^{[4
,7
]}

机构：

[1] Univ New Mexico, Coll Pharm, Div Pharm Practice, Albuquerque, NM 87131 USA

[2] Univ New Mexico, Dept Family Community Med, Albuquerque, NM 87131 USA

[3] Kaiser Permanente Med Ctr, Dept Allergy Immunol, San Diego, CA USA

[4] Univ Calif San Diego, Dept Pediat, La Jolla, CA 92093 USA

[5] Midwestern Univ, Glendale, AZ USA

[6] San Diego State Univ, Grad Sch Publ Hlth, San Diego, CA 92182 USA

[7] Univ Calif San Diego, Dept Family & Prevent Med, La Jolla, CA 92093 USA

来源：

JOURNAL OF ASTHMA | 2008年 / 45卷 / 05期

关键词：

asthma; fetal sex; pregnancy; asthma control; asthma exacerbation;

D O I：

10.1080/02770900801971826

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Asthma is a prevalent chronic disorder that might substantially complicate pregnancy. Some recent reports suggest that the presence of a female fetus might be associated with worse maternal asthma symptoms during pregnancy. We tested this hypothesis using the sample of 719 pregnant women with asthma prospectively enrolled in the OTIS study. The presence of a female fetus was associated with a higher incidence of hospitalizations for asthma during pregnancy (OR = 1.84; 95% CI: 1.05; 3.21) independent of maternal age, BMI, ethnicity, smoking, and socioeconomic status. The current study suggests that pregnant asthmatic women carrying a girl might be more susceptible to asthma exacerbations.

引用

页码：403 / 407

页数：5

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