Neutron scattering and HPLC study on L-ascorbic acid and its degradation

被引：13

作者：

Bellocco, E. ^{[1
]}

Barreca, D. ^{[1
]}

Lagana, G. ^{[1
]}

Leuzzi, U. ^{[1
]}

Migliardo, F. ^{[2
]}

La Torre, R. ^{[2
]}

Galli, G. ^{[2
]}

Galtleri, A. ^{[1
]}

Minutoli, L. ^{[3
]}

Squadrito, F. ^{[3
]}

机构：

[1] Univ Messina, Dept Organ & Biol Chem, Messina, Italy

[2] Univ Messina, Dept Phys, Messina, Italy

[3] Univ Messina, Dept Clin & Expt Med & Pharmacol, Messina, Italy

来源：

CHEMICAL PHYSICS | 2008年 / 345卷 / 2-3期

关键词：

vitamin C; degradation; diffusion; neutron scattering; HPLC;

D O I：

10.1016/j.chemphys.2007.07.006

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 [物理化学]; 081704 [应用化学];

摘要：

The present paper shows a systematic dynamic and kinetic study on L-ascorbic acid and its degradation at high temperature. The neutron scattering study allows, through the behavior of quasi-elastic neutron scattering (QENS) spectra, to characterize the diffusive dynamics Of L-ascorbic acid in water mixtures. Ascorbic acid undergoes degradation process at high temperature, but the presence of trehalose in solution markedly avoids ascorbic acid loss enhancing its t(1/2) (half life time), as determined by high performance liquid chromatography (HPLC). (C) 2007 Elsevier B.V. All rights reserved.

引用

页码：191 / 195

页数：5

共 17 条

[1]

[Anonymous], 1991, HDB VITAMINS

[2]

Bee M., 1988, Quasielastic Neutron Scattering

[3]

An assay for ascorbic acid based on polyaniline-coated microplates [J].