acute kidney injury;
definition;
staging;
biomarkers;
treatment of AKI;
D O I:
10.1053/j.ackd.2008.04.002
中图分类号:
R5 [内科学];
R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号:
1002 ;
100201 ;
摘要:
Changes in terminology and new consensus definitions of acute kidney injury (AKI) and stages of severity have simplified some of the problems in the clinical approach to this complex syndrome. Nevertheless, new proactive approaches to the diagnosis of kidney injury instead of kidney failure are required to allow clinical translation of successful therapies developed for experimental AKI. The recent development of novel urinary and plasma biomarkers, which predict kidney failure, has allowed the development of new paradigms for detection, prevention, and stage-specific treatment. (C) 2008 by the National Kidney Foundation, Inc. All rights reserved.
机构:
Yale Univ, Sch Med, Dept Med, New Haven, CT USAVAMC, Nephrol Sect, Clin Epidemiol Res Ctr, West Haven, CT 06516 USA
Coca, S. G.
Yalavarthy, R.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Colorado, Denver Hlth Med Ctr, Denver, CO USA
Hlth Sci Ctr, Denver, CO USAVAMC, Nephrol Sect, Clin Epidemiol Res Ctr, West Haven, CT 06516 USA
Yalavarthy, R.
Concato, J.
论文数: 0引用数: 0
h-index: 0
机构:
Yale Univ, Sch Med, Dept Med, New Haven, CT USAVAMC, Nephrol Sect, Clin Epidemiol Res Ctr, West Haven, CT 06516 USA
Concato, J.
Parikh, C. R.
论文数: 0引用数: 0
h-index: 0
机构:
VAMC, Nephrol Sect, Clin Epidemiol Res Ctr, West Haven, CT 06516 USA
Yale Univ, Sch Med, Clin Epidemiol Res Ctr, West Haven, CT 06510 USA
Yale Univ, Sch Med, Dept Med, New Haven, CT USAVAMC, Nephrol Sect, Clin Epidemiol Res Ctr, West Haven, CT 06516 USA
机构:
Yale Univ, Sch Med, Dept Med, New Haven, CT USAVAMC, Nephrol Sect, Clin Epidemiol Res Ctr, West Haven, CT 06516 USA
Coca, S. G.
Yalavarthy, R.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Colorado, Denver Hlth Med Ctr, Denver, CO USA
Hlth Sci Ctr, Denver, CO USAVAMC, Nephrol Sect, Clin Epidemiol Res Ctr, West Haven, CT 06516 USA
Yalavarthy, R.
Concato, J.
论文数: 0引用数: 0
h-index: 0
机构:
Yale Univ, Sch Med, Dept Med, New Haven, CT USAVAMC, Nephrol Sect, Clin Epidemiol Res Ctr, West Haven, CT 06516 USA
Concato, J.
Parikh, C. R.
论文数: 0引用数: 0
h-index: 0
机构:
VAMC, Nephrol Sect, Clin Epidemiol Res Ctr, West Haven, CT 06516 USA
Yale Univ, Sch Med, Clin Epidemiol Res Ctr, West Haven, CT 06510 USA
Yale Univ, Sch Med, Dept Med, New Haven, CT USAVAMC, Nephrol Sect, Clin Epidemiol Res Ctr, West Haven, CT 06516 USA