The integration of PET-CT scans from different hospitals into radiotherapy treatment planning

被引：45

作者：

Oellers, Michel ^{[1
]}

Bosmans, Geert ^{[1
]}

van Baardwijk, Angela ^{[1
]}

Dekker, Andre ^{[1
]}

Lambin, Philippe ^{[1
]}

Teule, Jaap ^{[2
]}

Thimister, Willie ^{[3
]}

Rhamy, Ali ^{[4
]}

De Ruysscher, Dirk ^{[1
]}

机构：

[1] Univ Hosp Maastricht, Dept Radiat Oncol MAASTRO, NL-6229 ET Maastricht, Netherlands

[2] Univ Hosp Maastricht, Dept Nucl Med, NL-6229 ET Maastricht, Netherlands

[3] Maastricht Hosp, Dept Nucl Med, Sittard, Netherlands

[4] Atrium Med Ctr, Dept Nucl Med, Heerlen, Netherlands

来源：

RADIOTHERAPY AND ONCOLOGY | 2008年 / 87卷 / 01期

关键词：

SUV; contouring; PET-CT; delineation; multi-center; radiotherapy planning;

D O I：

10.1016/j.radonc.2007.12.025

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Purpose: To integrate PET-CT scans from different hospitals into radiotherapy treatment planning. Methods and materials: A cylindrical phantom with spheres of different diameters was scanned on three different Siemens Biograph PET-CT scanners in three hospitals. The spheres and cylinder were filled with F-18-FDG such that different sphere-to-background (S/B) ratios were obtained. Scans were analyzed using dedicated software for automated delineation based on standardized uptake value (SUV) and using different reconstruction parameters. Results: SUV thresholding curves for different S/B ratios were obtained for the different scanners. Differences in SUV auto-contouring thresholds were found to be significant for PET-CT simulators from different radiotherapy and nuclear medicine departments. A change in PET reconstruction parameters showed a significant effect on the results. Conclusion: Synchronization of PET-CT imaging protocols between cooperating hospitals is important for reliable determination of SUV auto-contouring thresholds. Whenever this goal has been achieved automated SUV delineation based on a S/B ratio using PET-CT images from different institutions can reliably be performed using individually determined threshold curves. (C) 2008 Elsevier Ireland Ltd. All rights reserved.

引用

页码：142 / 146

页数：5

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