Interactions between rotavirus and gastrointestinal cells

被引:53
作者
Ciarlet, M [1 ]
Estes, MK [1 ]
机构
[1] Baylor Coll Med, Dept Mol Virol & Microbiol, Houston, TX 77030 USA
关键词
D O I
10.1016/S1369-5274(00)00232-0
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Rotaviruses are the leading cause of life-threatening diarrhea] disease in infants and in young animals worldwide. The outcome of rotavirus infection of intestinal epithelia] cells is more complex and involves induction of more diverse cellular responses than initially appreciated. Similar to bacteria, the pathogenesis of rotavirus-incluced disease involves an enterotoxin, activation of the enteric nervous system and malabsorption, suggesting that common mechanisms of pathogenesis may exist between viral and bacterial pathogens.
引用
收藏
页码:435 / 441
页数:7
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