Interactions between rotavirus and gastrointestinal cells

被引：53

作者：

Ciarlet, M ^{[1
]}

Estes, MK ^{[1
]}

机构：

[1] Baylor Coll Med, Dept Mol Virol & Microbiol, Houston, TX 77030 USA

来源：

CURRENT OPINION IN MICROBIOLOGY | 2001年 / 4卷 / 04期

关键词：

D O I：

10.1016/S1369-5274(00)00232-0

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Rotaviruses are the leading cause of life-threatening diarrhea] disease in infants and in young animals worldwide. The outcome of rotavirus infection of intestinal epithelia] cells is more complex and involves induction of more diverse cellular responses than initially appreciated. Similar to bacteria, the pathogenesis of rotavirus-incluced disease involves an enterotoxin, activation of the enteric nervous system and malabsorption, suggesting that common mechanisms of pathogenesis may exist between viral and bacterial pathogens.

引用

页码：435 / 441

页数：7

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