Tethering and tickling: a new role for the phosphatidylserine receptor

被引:97
作者
Somersan, S [1 ]
Bhardwaj, N [1 ]
机构
[1] Rockefeller Univ, Mol Neurooncol Lab, New York, NY 10021 USA
关键词
D O I
10.1083/jcb.200110066
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Several receptors are implicated in apoptotic cell (AC) uptake by phagocytic cells; however, their relative dominance in mammalian systems remains to be established. New studies shed light on the role of the phosphatidyl serine (PS) receptor (PSR). Ligation of PSR by PS on AC surfaces is considered essential for signaling uptake of ACs that are tethered to phagocytes via other receptors.
引用
收藏
页码:501 / 504
页数:4
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