Increased paraoxon detection by acetylcholinesterase inactivation with ionic liquid additives

被引：28

作者：

Zhang, CD ^{[1
]}

Malhotra, SV ^{[1
]}

机构：

[1] New Jersey Inst Technol, Dept Chem & Environm Sci, Newark, NJ 07102 USA

来源：

TALANTA | 2005年 / 67卷 / 03期

关键词：

paraoxon; acetylcholinesterase; ionic liquids; pyridinium; imidazolium;

D O I：

10.1016/j.talanta.2005.03.037

中图分类号：

O65 [分析化学];

学科分类号：

070302 [分析化学]; 081704 [应用化学];

摘要：

This is the first study using ionic liquids (ILs) as additive in the aqueous solvent medium for detection of paraoxon by acetylcholinesterase inhibition method. A systematic comparison of various ILs with organic solvents has been made. The aqueous buffer solution containing ionic liquid ethylpyridinium hexafluorophosphate [EtPy](+)[PF6](-) has been found to give the best results. The inhibition kinetic follows the first order model. Ionic liquids modified aqueous solutions show the potential to provide a promising and effective medium in detection of paraoxon with acetylcholinesterase. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：560 / 563

页数：4

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