PH-responsive biodegradable amphiphilic networks

被引：30

作者：

Zednik, Jiri ^{[1
]}

Riva, Raphael ^{[1
]}

Lussis, Perrine ^{[1
]}

Jerome, Christine ^{[1
]}

Jerome, Robert ^{[1
]}

Lecorate, Philippe ^{[1
]}

机构：

[1] Univ Liege, CERM, B-4000 Liege, Belgium

来源：

POLYMER | 2008年 / 49卷 / 03期

关键词：

ring-opening polymerization; click" chemistry; amphiphilic network;

D O I：

10.1016/j.polymer.2007.12.029

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Copper-mediated azide - alkyne Huisgen's 1,3-dipolar cycloaddition is a "click" reaction that was successfully used to prepare pH-responsive, amphiphilic and biodegradable networks. Indeed, this reaction proved to be very efficient in the "one pot" grafting of amino alkyne onto azide containing poly(epsilon-caprolactone) and the cross-linking of these chains by alpha,omega-dialkynyl poly(ethylene oxide). The pH-controlled release of guests hosted during the cross-linking step was illustrated with an entrapped model dye. (c) 2008 Elsevier Ltd. All rights reserved.

引用

页码：697 / 702

页数：6