Interaction networks for systems biology

被引：72

作者：

Bader, Samuel ^{[1
]}

Kuehner, Sebastian ^{[1
]}

Gavin, Anne-Claude ^{[1
]}

机构：

[1] European Mol Biol Lab, Struct & Computat Biol Unit, D-69117 Heidelberg, Germany

来源：

FEBS LETTERS | 2008年 / 582卷 / 08期

关键词：

interactome; AP-MS; yeast two-hybrid; protein complex; systems biology; protein-protein interaction;

D O I：

10.1016/j.febslet.2008.02.015

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Cellular functions are almost always the result of the coordinated action of several proteins, interacting in protein complexes, pathways or networks. Progress made in devising suitable tools for analysis of protein-protein interactions, have recently made it possible to chart interaction networks on a large-scale. The aim of this review is to provide a short overview of the most promising contributions of interaction networks to human biology, structural biology and human genetics. (C) 2008 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

引用

页码：1220 / 1224

页数：5

共 59 条

[1]

Gene prioritization through genomic data fusion [J].

Aerts, S ;

Lambrechts, D ;

Maity, S ;

Van Loo, P ;

Coessens, B ;

De Smet, F ;

Tranchevent, LC ;

De Moor, B ;

Marynen, P ;

Hassan, B ;

Carmeliet, P ;

Moreau, Y .

NATURE BIOTECHNOLOGY, 2006, 24 (05) :537-544

[2]

The molecular architecture of the nuclear pore complex [J].

Alber, Frank ;

Dokudovskaya, Svetlana ;

Veenhoff, Liesbeth M. ;

Zhang, Wenzhu ;

Kipper, Julia ;

Devos, Damien ;

Suprapto, Adisetyantari ;

Karni-Schmidt, Orit ;

Williams, Rosemary ;

Chait, Brian T. ;

Sali, Andrej ;

Rout, Michael P. .

NATURE, 2007, 450 (7170) :695-701

[3]

Determining the architectures of macromolecular assemblies [J].

Alber, Frank ;

Dokudovskaya, Svetlana ;

Veenhoff, Liesbeth M. ;

Zhang, Wenzhu ;

Kipper, Julia ;

Devos, Damien ;

Suprapto, Adisetyantari ;

Karni-Schmidt, Orit ;

Williams, Rosemary ;

Chait, Brian T. ;

Rout, Michael P. ;

Sali, Andrej .

NATURE, 2007, 450 (7170) :683-694

[4]

Structure-based assembly of protein complexes in yeast [J].

Aloy, P ;

Böttcher, B ;

Ceulemans, H ;

Leutwein, C ;

Mellwig, C ;

Fischer, S ;

Gavin, AC ;

Bork, P ;

Superti-Furga, G ;

Serrano, L ;

Russell, RB .

SCIENCE, 2004, 303 (5666) :2026-2029

[5]

A complex prediction:: three-dimensional model of the yeast exosome [J].

Aloy, P ;

Ciccarelli, FD ;

Leutwein, C ;

Gavin, AC ;

Superti-Furga, G ;

Bork, P ;

Böttcher, B ;

Russell, RB .

EMBO REPORTS, 2002, 3 (07) :628-635

[6]

Apert syndrome mutations in fibroblast growth factor receptor 2 exhibit increased affinity for FGF ligand [J].

Anderson, J ;

Burns, HD ;

Enriquez-Harris, P ;

Wilkie, AOM ;

Heath, JK .

HUMAN MOLECULAR GENETICS, 1998, 7 (09) :1475-1483

[7]

Protein-protein interactions and cancer: small molecules going in for the kill [J].

Arkin, M .

CURRENT OPINION IN CHEMICAL BIOLOGY, 2005, 9 (03) :317-324

[8]

From syndrome families to functional genomics [J].

Brunner, HG ;

van Driel, MA .

NATURE REVIEWS GENETICS, 2004, 5 (07) :545-551

[9]

Epstein-Barr virus and virus human protein interaction maps [J].

Calderwood, Michael A. ;

Venkatesan, Kavitha ;

Xing, Li ;

Chase, Michael R. ;

Vazquez, Alexel ;

Holthaus, Amy M. ;

Ewence, Alexandra E. ;

Li, Ning ;

Hirozane-Kishikawa, Tomoko ;

Hill, David E. ;

Vidal, Marc ;

Kieff, Elliott ;

Johannsen, Eric .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (18) :7606-7611

[10]

CHARBONNIER S, 2008, IN PRESS BIOTECHNOL, V14

← 1 2 3 4 5 6 →