Alginate: Properties and biomedical applications

被引：6354

作者：

Lee, Kuen Yong ^{[1
,2
,3
,4
]}

Mooney, David J. ^{[1
,2
]}

机构：

[1] Harvard Univ, Sch Engn Appl Sci, Cambridge, MA 02138 USA

[2] Harvard Univ, Wyss Inst, Cambridge, MA 02138 USA

[3] Hanyang Univ, Dept Bioengn, Seoul 133791, South Korea

[4] Hanyang Univ, Inst Bioengn & Biopharmaceut Res, Seoul 133791, South Korea

来源：

PROGRESS IN POLYMER SCIENCE | 2012年 / 37卷 / 01期

基金：

新加坡国家研究基金会;

关键词：

Biomaterial; Hydrogel; Wound dressing; Drug delivery; Tissue engineering; ENDOTHELIAL GROWTH-FACTOR; MESENCHYMAL STEM-CELLS; PERIPHERAL-NERVE REGENERATION; PARTIALLY OXIDIZED ALGINATE; VITRO CONTROLLED-RELEASE; IN-VIVO EVALUATION; SODIUM ALGINATE; CROSS-LINKING; N-ISOPROPYLACRYLAMIDE; FACTOR DELIVERY;

D O I：

10.1016/j.progpolymsci.2011.06.003

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 [高分子化学与物理];

摘要：

Alginate is a biomaterial that has found numerous applications in biomedical science and engineering due to its favorable properties, including biocompatibility and ease of gelation. Alginate hydrogels have been particularly attractive in wound healing, drug delivery, and tissue engineering applications to date, as these gels retain structural similarity to the extracellular matrices in tissues and can be manipulated to play several critical roles. This review will provide a comprehensive overview of general properties of alginate and its hydrogels. their biomedical applications, and suggest new perspectives for future studies with these polymers. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：106 / 126

页数：21

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