The preparation of chiral salicylaldehydes based on Kagan's ether

被引：6

作者：

Harmata, M ^{[1
]}

Wu, YH

Kahraman, M

Welch, CJ

机构：

[1] Univ Missouri, Dept Chem, Columbia, MO 65211 USA

[2] Regis Technol Inc, Morton Grove, IL 60053 USA

来源：

SYNTHETIC COMMUNICATIONS | 2001年 / 31卷 / 21期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1081/SCC-100106046

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two related routes to chiral salicylaldehydes which are derivatives of Kagan's ether have been developed. One route which is particularly simple begins with 2,6-diallylphenol. Facile conversion to a substituted benzofuran and assemblage of the basic framework of Kagan's ether is followed by an ozonolysis. of the benzofuran ring to reveal the hydroxyaldehyde functionality characteristic of salicylaldehydes.

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收藏

页码：3345 / 3359

页数：15

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