Trifluoromethylated amino alcohols as chiral ligands for highly enantioselective Reformatsky reaction

被引：42

作者：

Fujiwara, Y ^{[1
]}

Katagiri, T ^{[1
]}

Uneyama, K ^{[1
]}

机构：

[1] Okayama Univ, Fac Engn, Dept Appl Chem, Okayama 7008530, Japan

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 32期

关键词：

trifluoromethylated amino alcohol; chiral ligand; enantioselective Reformatsky reaction;

D O I：

10.1016/S0040-4039(03)01392-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

The enantioselective Reformatsky reaction of PhCHO was achieved by the use of trifluoromethylated amino alcohols as chiral ligands to afford the corresponding optically active beta-hydroxy ester with up to 90% ee. (C) 2003 Elsevier Ltd. All rights reserved.

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收藏

页码：6161 / 6163

页数：3

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