机构:Univ Calif San Francisco, Howard Hughes Med Inst, San Francisco, CA 94143 USA
Cohen, BE
Grabe, M
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机构:Univ Calif San Francisco, Howard Hughes Med Inst, San Francisco, CA 94143 USA
Grabe, M
Jan, LY
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Univ Calif San Francisco, Howard Hughes Med Inst, San Francisco, CA 94143 USAUniv Calif San Francisco, Howard Hughes Med Inst, San Francisco, CA 94143 USA
Jan, LY
[1
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机构:
[1] Univ Calif San Francisco, Howard Hughes Med Inst, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Dept Physiol, San Francisco, CA 94143 USA
[3] Univ Calif San Francisco, Dept Biochem, San Francisco, CA 94143 USA
The recent landmark structures of KvAP, a voltage-gated potassium (Kv) channel, provide the first high-resolution experimental structural models of this class of proteins. Previous extensive studies of Kv channels provide a means to evaluate and interpret the KvAP structures. In this minireview, we survey different experimental approaches to Kv channels and map these findings to KvAP, showing that the relationship between the KvAP structures and other Kv channels is uncertain.
机构:
Karolinska Inst, Dept Neurosci, Nobel Inst Neurophysiol, SE-17177 Stockholm, SwedenKarolinska Inst, Dept Neurosci, Nobel Inst Neurophysiol, SE-17177 Stockholm, Sweden
Elinder, F
Århem, P
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Karolinska Inst, Dept Neurosci, Nobel Inst Neurophysiol, SE-17177 Stockholm, SwedenKarolinska Inst, Dept Neurosci, Nobel Inst Neurophysiol, SE-17177 Stockholm, Sweden
Århem, P
Larsson, HP
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Karolinska Inst, Dept Neurosci, Nobel Inst Neurophysiol, SE-17177 Stockholm, SwedenKarolinska Inst, Dept Neurosci, Nobel Inst Neurophysiol, SE-17177 Stockholm, Sweden
机构:
Karolinska Inst, Dept Neurosci, Nobel Inst Neurophysiol, SE-17177 Stockholm, SwedenKarolinska Inst, Dept Neurosci, Nobel Inst Neurophysiol, SE-17177 Stockholm, Sweden
Elinder, F
Århem, P
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机构:
Karolinska Inst, Dept Neurosci, Nobel Inst Neurophysiol, SE-17177 Stockholm, SwedenKarolinska Inst, Dept Neurosci, Nobel Inst Neurophysiol, SE-17177 Stockholm, Sweden
Århem, P
Larsson, HP
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机构:
Karolinska Inst, Dept Neurosci, Nobel Inst Neurophysiol, SE-17177 Stockholm, SwedenKarolinska Inst, Dept Neurosci, Nobel Inst Neurophysiol, SE-17177 Stockholm, Sweden