Skin and nail changes in children with sickle cell anemia receiving hydroxyurea therapy

被引：33

作者：

O'Branski, EE

Ware, RE

Prose, NS

Kinney, TR

机构：

[1] Duke Univ, Med Ctr, Dept Pediat, Div Hematol Oncol, Durham, NC 27710 USA

[2] Duke Univ, Med Ctr, Pediat Sickle Cell Program, Durham, NC 27710 USA

[3] Duke Univ, Med Ctr, Dept Med, Div Dermatol, Durham, NC 27710 USA

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2001年 / 44卷 / 05期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1067/mjd.2001.113471

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Skin and nail changes from long-term hydroxyurea therapy are reported in adults. Skin and nail changes, including nail hyperpigmentation, longitudinal bands, and hyperpigmentation of the palms and other skin surfaces, developed in 7 children with sickle cell anemia after 6 to 16 weeks of hydroxyurea therapy. Cutaneous and nail changes may occur in children receiving hydroxyurea.

引用

页码：859 / 861

页数：3