Photochemical synthesis of a 4,5-dihydrofuroazetidinone, a novel β-lactam system

被引：6

作者：

Donati, D ^{[1
]}

Fusi, S ^{[1
]}

Ponticelli, F ^{[1
]}

机构：

[1] Univ Siena, Dept Chem, I-53100 Siena, Italy

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 52期

关键词：

isoxazole; anhydrobases; photochemistry; azetidinone; beta-lactam;

D O I：

10.1016/j.tetlet.2003.10.079

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2,4-Dimethyl-3-phenylisoxazole anhydrobases were easily prepared from the corresponding 5-chloroisoxazolium trifluoromethanesulfonate and carbon anions of 1,3-dioxo compounds in the presence of triethylamine. Photorearrangement of 2-(2,4-dimethyl-3-phenyl-2H-isoxazol-5-ylidene)malonic acid diethyl ester gave a 4,5-dihydrofuroazetidinone in good yield. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：9247 / 9250

页数：4

共 7 条

[1]

BECKER DA, 1993, SYNLETT, P866

[2] Stereoselective synthesis of a new enantiopure tricyclic β-lactam derivative via a tricarbonyl(η6-arene)chromium(0) complex [J].