Omega-3 fatty acids as a psychotherapeutic agent for a pregnant schizophrenic patient

被引：24

作者：

Su, KP

Shen, WW

Huang, SY ^{[1
]}

机构：

[1] Taipei Med Univ, Inst Nutr & Hlth Sci, Taipei, Taiwan

[2] Taipei Med Univ, Wan Fang Hosp, Dept Psychiat, Taipei, Taiwan

[3] Sch Med, Taipei, Taiwan

来源：

EUROPEAN NEUROPSYCHOPHARMACOLOGY | 2001年 / 11卷 / 04期

关键词：

omega-3 polyunsaturated fatty acids (PUFAs); pregnancy; schizophrenia; teratogenesis; ecosapentaenoic acid (EPA); docosahexaenoic acid (DHA);

D O I：

10.1016/S0924-977X(01)00098-0

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Because of the potential adverse events and teratogenesis of antipsychotic drugs, it is important to find a safe and effective treatment for pregnant women with severe mental illness. The membrane hypothesis of schizophrenia provides a rationale to treat symptoms of schizophrenia with omega-3 PUFAs. We report a 30-year-old married woman with chronic schizophrenia, who experienced an episode of acute exacerbation of psychotic symptoms during pregnancy. After entering into an open trial of omega-3 PUFAs monotherapy, she showed a dramatic improvement in both positive and negative symptoms of schizophrenia and a significant increase of omega-3 PUFA composition in erythrocyte membrane. There were no adverse effects in this treatment. Thus, omega-3 PUFAs could be both beneficial and therapeutic to pregnant schizophrenic women. (C) 2001 Elsevier Science BY All rights reserved.

引用

页码：295 / 299

页数：5

共 31 条

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