Clustering and switching on verbal fluency: the effects of focal frontal- and temporal-lobe lesions

被引:460
作者
Troyer, AK
Moscovitch, M
Winocur, G
Alexander, MP
Stuss, D
机构
[1] Baycrest Geriatr Ctr, Dept Psychol, Toronto, ON M6A 2E1, Canada
[2] Univ Toronto, Toronto, ON, Canada
[3] Baycrest Geriatr Ctr, Rotman Res Inst, N York, ON, Canada
[4] Univ Toronto, Erindale Coll, Mississauga, ON L5L 1C6, Canada
[5] Trent Univ, Peterborough, ON K9J 7B8, Canada
[6] Boston Univ, Boston Veterans Adm Med Ctr, Memory Disorders Ctr, Sch Med, Boston, MA 02215 USA
[7] Braintree Rehabil Hosp Network, Braintree, MA USA
基金
英国医学研究理事会;
关键词
focal brain lesions; temporal-lobe lesions; frontal-lobe lesions; semantic fluency; phonemic fluency;
D O I
10.1016/S0028-3932(97)00152-8
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
We examined the hypothesis that, on verbal fluency, clustering (i.e. generating words within subcategories) is related to temporal-lobe functioning, whereas switching (i.e. shifting between subcategories) is related to frontal-lobe functioning. Tests of phonemic and semantic fluency were administered to 53 patients with focal frontal-lobe lesions (FL), 23 patients with unilateral temporal-lobe lesions (TL) and 55 matched controls. Performance by FL patients was consistent with our hypothesis: in comparison to controls, patients with left-dorsolateral or superior-medial frontal lesions switched less frequently and produced normal cluster sizes on both phonemic and semantic fluency. Performance by TL patients was not consistent across fluency tasks and provided partial support for our hypothesis. On phonemic fluency, TI, patients were unimpaired on both switching and clustering. On semantic fluency, TL patients were impaired on switching in comparison to controls and left TL patients produced smaller clusters than right TL patients. The best indices for discriminating the patient groups, therefore, were phonemic-fluency switching (impaired only with frontal lesions) and semantic-fluency clustering (impaired only with temporal-lobe lesions). (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:499 / 504
页数:6
相关论文
共 28 条
[1]   DIFFERENTIAL BEHAVIORAL EFFECTS IN FRONTAL LOBE DISEASE [J].
BENTON, AL .
NEUROPSYCHOLOGIA, 1968, 6 (01) :53-&
[2]   WORD FLUENCY AND BRAIN DAMAGE [J].
BORKOWSKI, JG ;
BENTON, AL ;
SPREEN, O .
NEUROPSYCHOLOGIA, 1967, 5 (02) :135-+
[3]   A ROLE FOR THE HIPPOCAMPUS IN CARD SORTING [J].
CORCORAN, R ;
UPTON, D .
CORTEX, 1993, 29 (02) :293-304
[4]   FRONTAL VERBAL AMNESIA - PHONOLOGICAL AMNESIA [J].
COSLETT, HB ;
BOWERS, D ;
VERFAELLIE, M ;
HEILMAN, KM .
ARCHIVES OF NEUROLOGY, 1991, 48 (09) :949-955
[5]  
COSTELLO AD, 1989, CORTEX, V25, P103
[6]   SEVERE FRONTAL SYNDROME-ASSOCIATED WITH INFARCTS OF THE LEFT ANTERIOR CINGULATE GYRUS AND THE HEAD OF THE RIGHT CAUDATE-NUCLEUS - A CLINICOPATHOLOGICAL CASE [J].
DEGOS, JD ;
DAFONSECA, N ;
GRAY, F ;
CESARO, P .
BRAIN, 1993, 116 :1541-1548
[7]   CONTRIBUTIONS OF ANTERIOR CINGULATE CORTEX TO BEHAVIOUR [J].
DEVINSKY, O ;
MORRELL, MJ ;
VOGT, BA .
BRAIN, 1995, 118 :279-306
[8]   A BIRD IS A BIRD IS A BIRD - MAKING REFERENCE WITHIN AND WITHOUT SUPERORDINATE CATEGORIES [J].
GROSSMAN, M .
BRAIN AND LANGUAGE, 1981, 12 (02) :313-331
[9]   SEMANTIC DEMENTIA - PROGRESSIVE FLUENT APHASIA WITH TEMPORAL-LOBE ATROPHY [J].
HODGES, JR ;
PATTERSON, K ;
OXBURY, S ;
FUNNELL, E .
BRAIN, 1992, 115 :1783-1806
[10]   COGNITIVE IMPAIRMENT FOLLOWING FRONTAL-LOBE DAMAGE AND ITS RELEVANCE TO HUMAN AMNESIA [J].
JANOWSKY, JS ;
SHIMAMURA, AP ;
KRITCHEVSKY, M ;
SQUIRE, LR .
BEHAVIORAL NEUROSCIENCE, 1989, 103 (03) :548-560