Moderate consumption of olive oil by healthy European men reduces systolic blood pressure in non-Mediterranean participants

被引:49
作者
Bondia-Pons, Isabel
Schroder, Helmut
Covas, Maria-Isabel
Castellote, Ana I.
Kaikkonen, Jari
Poulsen, Henrik E.
Gaddi, Antonio V.
Machowetz, Anja
Kiesewetter, Holger
Lopez-Sabater, M. Carmen
机构
[1] Univ Barcelona, Fac Pharm, Dept Nutr & Food Sci, Ctr Reference Technol Food, E-08028 Barcelona, Spain
[2] Inst Municipal Invest Med, Lipids & Cardiovasc Epidemiol Unit, E-08003 Barcelona, Spain
[3] Oy Jurilab Ltd, F-70210 Kuopio, Finland
[4] Univ Copenhagen Hosp, Rigshosp, Dept Clin Pharmacol, DK-2200 Copenhagen, Denmark
[5] Univ Bologna, Atherosclerosis Ctr CG Descovich, IT-41038 Bologna, Italy
[6] German Inst Nutr Potsdam Rehbruecke, Dept Intervent Studies, D-14558 Nuthetal, Germany
[7] Univ Med Berlin, Charite, D-10117 Berlin, Germany
关键词
D O I
10.1093/jn/137.1.84
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
We evaluated the effects of a moderate consumption of olive oil on lipid profile, BMI, and blood pressure (BP) in a group of 160 healthy men from non-Mediterranean regions [Northern Europe (n=50; Finland and Denmark) and Central Europe (n=60; Germany)] and Mediterranean regions [Southern Europe (n=45; Italy and Spain)]. The study was a randomized, crossover trial with 3 intervention periods of 3 wk and 2 wash-out periods of 2 wk. At the intervention periods, 3 similar olive oils (25 mL/d), differing only in their phenolic concentration, were administered to the healthy volunteers. Plasma oleic acid levels increased 2-3% (P < 0.05) in men from populations with lower habitual olive oil intakes (Northern and Central Europe). General linear models showed that the administration of the sequence of the 3 olive oils was responsible for a 3% decrease in systolic BP (SBP) (P < 0.05), but not in diastolic BP, in the non-Mediterranean subjects. Multivariate analysis indicated that the lipid profile did not change in either Mediterranean or non-Mediterranean men due to the olive oil intervention. The results of this study suggest that a moderate consumption of olive oil may be used as an effective tool to reduce SBP of healthy men who do not typically consume a Mediterranean diet. However, additional longer trials are necessary for confirmation. J. Nutr. 137: 84-87, 2007.
引用
收藏
页码:84 / 87
页数:4
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