Regulation of transcription of cellulases- and hemicellulases-encoding genes in Aspergillus niger and Hypocrea jecorina (Trichoderma reesei)

被引：225

作者：

Stricker, Astrid R. ^{[2
]}

Mach, Robert L. ^{[2
]}

de Graaff, Leo H. ^{[1
]}

机构：

[1] Univ Wageningen & Res Ctr, Microbiol Lab, Fungal Genom Grp, NL-6703 HB Wageningen, Netherlands

[2] TU Wien, Inst Chem Engn, A-1060 Vienna, Austria

来源：

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY | 2008年 / 78卷 / 02期

关键词：

transcriptional regulation; gene expression; xylanase; cellulase;

D O I：

10.1007/s00253-007-1322-0

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The filamentous fungi Aspergillus niger and Hypocrea jecorina (Trichoderma reesei) have been the subject of many studies investigating the mechanism of transcriptional regulation of hemicellulase- and cellulase-encoding genes. The transcriptional regulator XlnR that was initially identified in A. niger as the transcriptional regulator of xylanase-encoding genes controls the transcription of about 20-30 genes encoding hemicellulases and cellulases. The orthologous xyr1 (xylanase regulator 1-encoding) gene product of H. jecorina has a similar function as XlnR, although at points, the mechanisms seems to be different. Specifically in H. jecorina, the interaction of Xyr1 and the co-regulators Ace1 and Ace2 in the regulation of transcription of xylanases and cellulases has been studied. This paper describes the similarities and differences in the transcriptional regulation of expression of hemicellulases and cellulases in A. niger and H. jecorina.

引用

页码：211 / 220

页数：10