Type 17 T-helper cells might be a promising therapeutic target for systemic lupus erythematosus

被引:56
作者
Pan, Hai Feng
Ye, Dong Qing
Li, Xiang Pei [1 ]
机构
[1] Anhui Prov Hosp, Dept Rheumatol, Hefei, Anhui, Peoples R China
来源
NATURE CLINICAL PRACTICE RHEUMATOLOGY | 2008年 / 4卷 / 07期
关键词
D O I
10.1038/ncprheum0815
中图分类号
R5 [内科学];
学科分类号
1002 [临床医学]; 100201 [内科学];
摘要
[No abstract available]
引用
收藏
页码:352 / 353
页数:2
相关论文
共 14 条
[1]
Mechanisms of disease: the complement system and the pathogenesis of systemic lupus erythematosus [J].
Cook, H. Terence ;
Botto, Marina .
NATURE CLINICAL PRACTICE RHEUMATOLOGY, 2006, 2 (06) :330-337
[2]
T-helper cell intrinsic defects in lupus that break peripheral tolerance to nuclear autoantigens [J].
Datta, SK ;
Zhang, L ;
Xu, LT .
JOURNAL OF MOLECULAR MEDICINE-JMM, 2005, 83 (04) :267-278
[3]
Dong GF, 2003, CHINESE MED J-PEKING, V116, P543
[4]
Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice [J].
Hsu, Hui-Chen ;
Yang, PingAr ;
Wang, John ;
Wu, Qi ;
Myers, Riley ;
Chen, Jian ;
Yi, John ;
Guentert, Tanja ;
Tousson, Albert ;
Stanus, Andrea L. ;
Le, Thuc-vy L. ;
Lorenz, Robin G. ;
Xu, Hui ;
Kolls, Jay K. ;
Carter, Robert H. ;
Chaplin, David D. ;
Williams, Robert W. ;
Mountz, John D. .
NATURE IMMUNOLOGY, 2008, 9 (02) :166-175
[5]
Interleukin (IL)-23 receptor is a major susceptibility gene for Graves' ophthalmopathy: The IL-23/T-helper 17 axis extends to thyroid autoimmunity [J].
Huber, Amanda K. ;
Jacobson, Eric M. ;
Jazdzewski, Krystian ;
Concepcion, Erlinda S. ;
Tomer, Yaron .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2008, 93 (03) :1077-1081
[6]
New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions [J].
Hunter, CA .
NATURE REVIEWS IMMUNOLOGY, 2005, 5 (07) :521-531
[7]
The IL-23/Th17axis:: therapeutic targets for autoimmune inflammation [J].
Kikly, Kristine ;
Liu, Ling ;
Na, Songqing ;
Sedgwick, Jonathon D. .
CURRENT OPINION IN IMMUNOLOGY, 2006, 18 (06) :670-675
[8]
Th17 cells: Effector T cells with inflammatory properties [J].
Korn, Thomas ;
Oukka, Mohamed ;
Kuchroo, Vijay ;
Bettelli, Estelle .
SEMINARS IN IMMUNOLOGY, 2007, 19 (06) :362-371
[9]
Interleukin-17: A new paradigm in inflammation, autoimmunity, and therapy [J].
Kramer, Jill M. ;
Gaffen, Sarah L. .
JOURNAL OF PERIODONTOLOGY, 2007, 78 (06) :1083-1093
[10]
Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion [J].
Lubberts, E ;
Koenders, MI ;
Oppers-Walgreen, B ;
van den Bersselaar, L ;
Coenen-de Roo, CJJ ;
Joosten, LAB ;
van den Berg, WB .
ARTHRITIS AND RHEUMATISM, 2004, 50 (02) :650-659