Synthetic studies on apoptolidin: synthesis of the C1-C21 macrolide fragment

被引：46

作者：

Toshima, K ^{[1
]}

Arita, T ^{[1
]}

Kato, K ^{[1
]}

Tanaka, D ^{[1
]}

Matsumura, S ^{[1
]}

机构：

[1] Keio Univ, Fac Sci & Technol, Dept Appl Chem, Kohoku Ku, Yokohama, Kanagawa 2238522, Japan

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 50期

关键词：

apoptolidin; apoptosis; macrolide; macrocyclization;

D O I：

10.1016/S0040-4039(01)01948-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The stereoselective and convergent synthesis of the C1-C21 macrocyclic segment. (2) of the apoptosis inducing macrolide antibiotic, apoptolidin (1), is described. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：8873 / 8876

页数：4

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