Glycerol as a promoting medium for electrophilic activation of aldehydes: catalyst-free synthesis of di(indolyl)methanes, xanthene-1,8(2H)-diones and 1-oxo-hexahydroxanthenes

被引：123

作者：

He, Fei ^{[1
]}

Li, Peng ^{[1
]}

Gu, Yanlong ^{[1
,2
]}

Li, Guangxing ^{[1
,2
]}

机构：

[1] Huazhong Univ Sci & Technol, Inst Phys Chem & Ind Catalysis, Sch Chem & Chem Engn, Wuhan 430074, Peoples R China

[2] Huazhong Univ Sci & Technol, Hubei Key Lab Mat Chem & Serv Failure, Wuhan 430074, Peoples R China

来源：

GREEN CHEMISTRY | 2009年 / 11卷 / 11期

关键词：

BIS-INDOLYLMETHANES; EFFICIENT SYNTHESIS; CARBONYL-COMPOUNDS; RATIONAL DESIGN; DERIVATIVES; SOLVENT; INDOLES; MILD; BIS(1H-INDOL-3-YL)METHANES; BIS(INDOLYL)METHANES;

D O I：

10.1039/b916015a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Glycerol was used, for the first time, as a green and effective promoting medium for electrophilic activation of aldehydes, and with which, a catalyst-free system for some reactions that conventionally carried out using acid catalysts, such as synthesis of di(indolyl)methanes, 3,4,5,6,7,9-hexahydro-9-aryl-1H-xanthene-1,8(2H)-dione and 1-oxo-hexahydroxanthenes, was developed.

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页码：1767 / 1773

页数：7

相关论文

共 37 条

[1]

[Anonymous], GREEN CHEM

[2] The future of energy supply: Challenges and opportunities [J].

Armaroli, Nicola ;

Balzani, Vincenzo .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (1-2) :52-66

[3] A convenient method of synthesis of bis-indolylmethanes:: Indium trichloride catalyzed reactions of indole with aldehydes and Schiff's bases. [J].

Babu, G ;

Sridhar, N ;

Perumal, PT .

SYNTHETIC COMMUNICATIONS, 2000, 30 (09) :1609-1614

[4] Improved utilisation of renewable resources: New important derivatives of glycerol [J].

Behr, Arno ;

Eilting, Jens ;

Irawadi, Ken ;

Leschinski, Julia ;

Lindner, Falk .

GREEN CHEMISTRY, 2008, 10 (01) :13-30

[5] Synthesis and properties of glycerylimidazolium based ionic liquids: a promising class of task-specific ionic liquids [J].

Bellina, Fabio ;

Bertoli, Alessandra ;

Melai, Bernardo ;

Scalesse, Francesca ;

Signori, Francesca ;

Chiappe, Cinzia .

GREEN CHEMISTRY, 2009, 11 (05) :622-629

[6] Dry reaction of indoles with carbonyl compounds on montmorillonite K10 clay: a mild, expedient synthesis of diindolylalkanes and vibrindole A [J].

Chakrabarty, M ;

Ghosh, N ;

Basak, R ;

Harigaya, Y .

TETRAHEDRON LETTERS, 2002, 43 (22) :4075-4078

[7] Chemical routes for the transformation of biomass into chemicals [J].

Corma, Avelino ;

Iborra, Sara ;

Velty, Alexandra .

CHEMICAL REVIEWS, 2007, 107 (06) :2411-2502

[8] Amberlyst-15: An efficient reusable heterogeneous catalyst for the synthesis of 1,8-dioxo-octahydroxanthenes and 1,8-dioxo-decahydroacridines [J].

Das, B ;

Thirupathi, P ;

Mahender, I ;

Reddy, VS ;

Rao, YK .

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 2006, 247 (1-2) :233-239

[9] Silica-supported Phosphomolybdic Acid-catalyzed Efficient Synthesis of 1,8-Dioxooctahydroxanthene and Tetrahydrochromene Derivatives [J].

Das, Biswanath ;

Krishnaiah, Martha ;

Laxminarayana, Keetha ;

Damodar, Kongara ;

Kumar, Duddukuri Nandan .

CHEMISTRY LETTERS, 2008, 37 (09) :1000-1001

[10] Amberlyst 15 catalyzed synthesis of indole-pyrazole based tri(hetero)arylmethanes [J].

Farhanullah ;

Sharon, A ;

Maulik, PR ;

Ram, VJ .

TETRAHEDRON LETTERS, 2004, 45 (26) :5099-5102

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