Glycerol as a promoting medium for electrophilic activation of aldehydes: catalyst-free synthesis of di(indolyl)methanes, xanthene-1,8(2H)-diones and 1-oxo-hexahydroxanthenes

被引：123

作者：

He, Fei ^{[1
]}

Li, Peng ^{[1
]}

Gu, Yanlong ^{[1
,2
]}

Li, Guangxing ^{[1
,2
]}

机构：

[1] Huazhong Univ Sci & Technol, Inst Phys Chem & Ind Catalysis, Sch Chem & Chem Engn, Wuhan 430074, Peoples R China

[2] Huazhong Univ Sci & Technol, Hubei Key Lab Mat Chem & Serv Failure, Wuhan 430074, Peoples R China

来源：

GREEN CHEMISTRY | 2009年 / 11卷 / 11期

关键词：

BIS-INDOLYLMETHANES; EFFICIENT SYNTHESIS; CARBONYL-COMPOUNDS; RATIONAL DESIGN; DERIVATIVES; SOLVENT; INDOLES; MILD; BIS(1H-INDOL-3-YL)METHANES; BIS(INDOLYL)METHANES;

D O I：

10.1039/b916015a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Glycerol was used, for the first time, as a green and effective promoting medium for electrophilic activation of aldehydes, and with which, a catalyst-free system for some reactions that conventionally carried out using acid catalysts, such as synthesis of di(indolyl)methanes, 3,4,5,6,7,9-hexahydro-9-aryl-1H-xanthene-1,8(2H)-dione and 1-oxo-hexahydroxanthenes, was developed.

引用

页码：1767 / 1773

页数：7

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