Evidence for the efficacy of artesunate in asymptomatic Plasmodium malariae infections

被引：14

作者：

Borrmann, S

Szlezák, N

Binder, RK

Missinou, MA

Lell, B

Kremsner, PG

机构：

[1] Albert Schweitzer Hosp, Med Res Unit, Lambarene, Gabon

[2] Univ Tubingen, Dept Parasitol, Inst Trop Med, D-72074 Tubingen, Germany

[3] Harvard Univ, John F Kennedy Sch Govt, Cambridge, MA 02138 USA

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2002年 / 50卷 / 05期

关键词：

Plasmodium malariae; artesunate; chemotherapy; malaria; Gabon;

D O I：

10.1093/jac/dkf200

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

This study evaluated the efficacy and safety of a 3-day course of artesunate (4 mg/kg/day) for asymptomatic Plasmodium malariae infections. The parasitological cure rates on days 7 and 56 in the group treated with artesunate were 100% and 83%, respectively, compared with no cure in the placebo group (P < 0.0001).

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收藏

页码：751 / 754

页数：4

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