Texture analysis of hippocampal sclerosis

被引:58
作者
Bonilha, L
Kobayashi, E
Castellano, G
Coelho, T
Tinois, E
Cendes, F
Li, LM
机构
[1] Univ Estadual Campinas, Dept Neurol, Sch Med, Campinas, SP, Brazil
[2] Univ Estadual Campinas, Ctr Biomed Engn, Campinas, SP, Brazil
关键词
epilepsy MRI; texture; hippocampal sclerosis;
D O I
10.1111/j.0013-9580.2003.27103.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Mesial temporal lobe epilepsy (MTLE) is frequently associated with refractory seizures and pathologic features of hippocampal sclerosis (HS). Quantitative magnetic resonance imaging (MRI) techniques can improve the detection and quantification of HS. The objective of this study was to evaluate whether MRI texture analysis can detect hippocampal abnormalities in patients with pathologically proven HS. Methods: Nineteen consecutive patients who underwent surgery for refractory unilateral MTLE and had HS diagnosed on histopathology (12 right and seven left) had their preoperative MRIs evaluated. We performed texture analysis in 3-mm corona) T-1-IR MRIs, focusing on the, hippocampal head, by using the software MAZDA. Data were compared with those of a group of 78 normal hippocampi from 39 healthy adult volunteers through multivariate analysis of variance and selection of the most significant texture parameters. Results: Overall, almost all parameters of texture could discriminate the group of hippocampi with HS and the group of contralateral hippocampi from the group of normal hippocampi, but the post hoc comparison showed no differences between HS and contralateral hippocampi. Conclusions: These results provide evidence of texture alteration in MRIs of hippocampi with HS and corroborate the hypothesis of bilaterality of hippocampal damage in patients with MTLE, but further studies are needed to investigate the lateralization power of texture analysis.
引用
收藏
页码:1546 / 1550
页数:5
相关论文
共 16 条
[1]   T2 relaxometry can lateralize mesial temporal lobe epilepsy in patients with normal MRI [J].
Bernasconi, A ;
Bernasconi, N ;
Caramanos, Z ;
Reutens, DC ;
Andermann, F ;
Dubeau, F ;
Tampieri, D ;
Pike, BG ;
Arnold, DL .
NEUROIMAGE, 2000, 12 (06) :739-746
[2]   Texture analysis and morphological processing of magnetic resonance imaging assist detection of focal cortical dysplasia in extra-temporal partial epilepsy [J].
Bernasconi, A ;
Antel, SB ;
Collins, DL ;
Bernasconi, N ;
Olivier, A ;
Dubeau, F ;
Pike, GB ;
Andermann, F ;
Arnold, DL .
ANNALS OF NEUROLOGY, 2001, 49 (06) :770-775
[3]   MRI VOLUMETRIC MEASUREMENT OF AMYGDALA AND HIPPOCAMPUS IN TEMPORAL-LOBE EPILEPSY [J].
CENDES, F ;
ANDERMANN, F ;
GLOOR, P ;
EVANS, A ;
JONESGOTMAN, M ;
WATSON, C ;
MELANSON, D ;
OLIVIER, A ;
PETERS, T ;
LOPESCENDES, I ;
LEROUX, G .
NEUROLOGY, 1993, 43 (04) :719-725
[4]  
Gloor P, 1991, EPILEPSY SURG, P689
[5]   TEXTURAL FEATURES FOR IMAGE CLASSIFICATION [J].
HARALICK, RM ;
SHANMUGAM, K ;
DINSTEIN, I .
IEEE TRANSACTIONS ON SYSTEMS MAN AND CYBERNETICS, 1973, SMC3 (06) :610-621
[6]   TEXTURED IMAGE SEGMENTATION BY CONTEXT ENHANCED CLUSTERING [J].
HU, Y ;
DENNIS, TJ .
IEE PROCEEDINGS-VISION IMAGE AND SIGNAL PROCESSING, 1994, 141 (06) :413-421
[7]   The prognosis for control of seizures with medications in patients with MRI evidence for mesial temporal sclerosis [J].
Kim, WJ ;
Park, SC ;
Lee, SJ ;
Lee, JH ;
Kim, JY ;
Lee, BI ;
Kim, DI .
EPILEPSIA, 1999, 40 (03) :290-293
[8]  
KJAER L, 1995, ACTA RADIOL, V36, P127
[9]  
Kuzniecky R., 1995, MAGNETIC RESONANCE E
[10]   TISSUE CHARACTERIZATION BY MAGNETIC-RESONANCE SPECTROSCOPY AND IMAGING - RESULTS OF A CONCERTED RESEARCH-PROJECT OF THE EUROPEAN-ECONOMIC-COMMUNITY .8. MR IMAGE TEXTURE ANALYSIS - AN APPROACH TO TISSUE CHARACTERIZATION [J].
LERSKI, RA ;
STRAUGHAN, K ;
SCHAD, LR ;
BOYCE, D ;
BLUML, S ;
ZUNA, I .
MAGNETIC RESONANCE IMAGING, 1993, 11 (06) :873-887