Generalized linear additive smooth structures

被引:55
作者
Eilers, PHC [1 ]
Marx, BD
机构
[1] Leiden Univ, Med Ctr, Dept Med Stat, NL-2300 RC Leiden, Netherlands
[2] Louisiana State Univ, Dept Expt Stat, Baton Rouge, LA 70803 USA
关键词
generalized additive models; multivariate calibration; P-splines; signal regression; varying-coefficient models;
D O I
10.1198/106186002844
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
This article proposes a practical modeling approach that can accommodate a rich variety of predictors, united in a generalized linear model (GLM) setting. In addition to the usual ANOVA-type or covariate linear (L) predictors, we consider modeling any combination of smooth additive (G) components, varying coefficient (V) components, and (discrete representations of) signal (S) components. We assume that G is, and the coefficients of V and S are, inherently smooth-projecting each of these onto B-spline bases using a modest number of equally spaced knots. Enough knots are used to ensure more flexibility than needed; further smoothness is achieved through a difference penalty on adjacent B-spline coefficients (P-splines). This linear re-expression allows all of the parameters associated with these components to be estimated simultaneously in one large GLM through penalized likelihood. Thus, we have the advantage of avoiding both the backfitting algorithm and complex knot selection schemes. We regulate the flexibility of each component through a separate penalty parameter that is optimally chosen based on cross-validation or an information criterion.
引用
收藏
页码:758 / 783
页数:26
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