LRRK2 haplotype analyses in European and North African families with Parkinson disease:: A common founder for the G2019S mutation dating from the 13th century

被引:108
作者
Lesage, S
Leutenegger, AL
Ibanez, P
Janin, S
Lohmann, E
Dürr, A
Brice, A
机构
[1] Hop La Pitie Salpetriere, INSERM, U679, F-75651 Paris, France
[2] Hop La Pitie Salpetriere, Dept Genet, F-75651 Paris, France
[3] CHU Pitie Salpetriere, Federat Neurol, Paris, France
[4] Unite Format & Rech Pierre & Marie Curie, Paris, France
关键词
D O I
10.1086/432422
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
引用
收藏
页码:330 / 332
页数:3
相关论文
共 10 条
  • [1] Merlin-rapid analysis of dense genetic maps using sparse gene flow trees
    Abecasis, GR
    Cherny, SS
    Cookson, WO
    Cardon, LR
    [J]. NATURE GENETICS, 2002, 30 (01) : 97 - 101
  • [2] Di Fonzo A, 2005, LANCET, V365, P412
  • [3] EXCOFFIER L, 1995, MOL BIOL EVOL, V12, P921
  • [4] Estimating the age of rare disease mutations: the example of Triple-A syndrome
    Genin, E
    Tullio-Pelet, A
    Begeot, F
    Lyonnet, S
    Abel, L
    [J]. JOURNAL OF MEDICAL GENETICS, 2004, 41 (06) : 445 - 449
  • [5] Common LRRK2 mutation in idiopathic Parkinson's disease
    Gilks, WP
    Abou-Sleiman, PM
    Gandhi, S
    Jain, S
    Singleton, A
    Lees, AJ
    Shaw, K
    Bhatia, KP
    Bonifati, V
    Quinn, NP
    Lynch, J
    Healy, DG
    Holton, JL
    Revesz, T
    Wood, NW
    [J]. LANCET, 2005, 365 (9457) : 415 - 416
  • [6] Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism:: Evidence of a common founder across European populations
    Kachergus, J
    Mata, IF
    Hulihan, M
    Taylor, JP
    Lincoln, S
    Aasly, J
    Gibson, JM
    Ross, OA
    Lynch, T
    Wiley, J
    Payami, H
    Nutt, J
    Maraganore, DM
    Czyzewski, K
    Styczynska, M
    Wszolek, ZK
    Farrer, MJ
    Toft, M
    [J]. AMERICAN JOURNAL OF HUMAN GENETICS, 2005, 76 (04) : 672 - 680
  • [7] The G2019SLRRK2 mutation in autosomal dominant European and North African Parkinson's disease is frequent and its penetrance is age-dependant
    Lesage, S
    Ibanez, P
    Lohmann, E
    Agid, Y
    Dürr, A
    Brice, A
    [J]. NEUROLOGY, 2005, 64 (10) : 1826 - 1826
  • [8] Genetic screening for a single common LRRK2 mutation in familial Parkinson's disease
    Nichols, WC
    Pankratz, N
    Hernandez, D
    Paisán-Ruíz, C
    Jain, S
    Halter, CA
    Michaels, VE
    Reed, T
    Rudolph, A
    Shults, CW
    Singleton, A
    Foroud, T
    [J]. LANCET, 2005, 365 (9457) : 410 - 412
  • [9] Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease
    Paisán-Ruíz, C
    Jain, S
    Evans, EW
    Gilks, WP
    Simón, J
    van der Brug, M
    de Munain, AL
    Aparicio, S
    Gil, AM
    Khan, N
    Johnson, J
    Martinez, JR
    Nicholl, D
    Carrera, IM
    Pena, AS
    de Silva, R
    Lees, A
    Martí-Massó, JF
    Pérez-Tur, J
    Wood, NW
    Singleton, AB
    [J]. NEURON, 2004, 44 (04) : 595 - 600
  • [10] Mutations in LRRK2 cause autosomal-dominant Parkinsonism with pleomorphic pathology
    Zimprich, A
    Biskup, S
    Leitner, P
    Lichtner, P
    Farrer, M
    Lincoln, S
    Kachergus, J
    Hulihan, M
    Uitti, RJ
    Calne, DB
    Stoessl, AJ
    Pfeiffer, RF
    Patenge, N
    Carbajal, IC
    Vieregge, P
    Asmus, F
    Müller-Myhsok, B
    Dickson, DW
    Meitinger, T
    Strom, TM
    Wszolek, ZK
    Gasser, T
    [J]. NEURON, 2004, 44 (04) : 601 - 607