CARs on Track in the Clinic

被引：98

作者：

Kohn, Donald B. ^{[1
,2
]}

Dotti, Gianpietro ^{[3
,4
]}

Brentjens, Renier ^{[5
,6
]}

Savoldo, Barbara ^{[3
,4
]}

Jensen, Michael ^{[7
]}

Cooper, Laurence J. N. ^{[8
]}

June, Carl H. ^{[9
,10
]}

Rosenberg, Steven ^{[11
]}

Sadelain, Michel ^{[5
,6
]}

Heslop, Helen E. ^{[3
,4
]}

机构：

[1] Univ Calif Los Angeles, Dept Microbiol Immunol & Mol Genet, Los Angeles, CA 90095 USA

[2] Univ Calif Los Angeles, Dept Pediat, Los Angeles, CA 90095 USA

[3] Methodist Hosp, Baylor Coll Med, Ctr Cell & Gene Therapy, Houston, TX 77030 USA

[4] Texas Childrens Hosp, Houston, TX 77030 USA

[5] Mem Sloan Kettering Canc Ctr, Dept Med, New York, NY 10021 USA

[6] Mem Sloan Kettering Canc Ctr, Ctr Cell Engn, New York, NY 10021 USA

[7] Seattle Childrens Res Inst, Ctr Immun & Immunotherapies, Seattle, WA USA

[8] Univ Texas MD Anderson Canc Ctr, Div Pediat, Houston, TX 77030 USA

[9] Univ Penn, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA

[10] Univ Penn, Abramson Family Canc Res Inst, Philadelphia, PA 19104 USA

[11] NCI, Surg Branch, NIH, Bethesda, MD 20892 USA

来源：

MOLECULAR THERAPY | 2011年 / 19卷 / 03期

关键词：

CHIMERIC ANTIGEN RECEPTOR; CYTOTOXIC T-LYMPHOCYTES; ADOPTIVE TRANSFER; ANTITUMOR-ACTIVITY; ADVERSE EVENT; CELLS; SPECIFICITY; SURVIVAL; GENE; PERSISTENCE;

D O I：

10.1038/mt.2011.1

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 [微生物学]; 090105 [作物生产系统与生态工程];

摘要：

引用

页码：432 / 438

页数：7

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