Wide Dissemination of Pseudomonas aeruginosa Producing β-Lactamase blaKPC-2 Gene in Colombia

被引：62

作者：

Cuzon, Gaelle ^{[1
,2
]}

Naas, Thierry ^{[1
,2
]}

Villegas, Maria-Virginia ^{[3
]}

Correa, Adriana ^{[3
]}

Quinn, John P. ^{[4
]}

Nordmann, Patrice ^{[1
,2
]}

机构：

[1] Hop Bicetre, Assistance Publ Hop Paris, Serv Bacteriol Virol, INSERM Emerging Resistance Antibiot U914, F-94275 Le Kremlin Bicetre, France

[2] Fac Med Paris Sud, Paris, France

[3] Int Ctr Med Res & Training, Cali, Colombia

[4] Pfizer Global Res & Dev, Groton, CT USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2011年 / 55卷 / 11期

基金：

英国惠康基金;

关键词：

COMPLETE NUCLEOTIDE-SEQUENCE; KLEBSIELLA-PNEUMONIAE; KPC; RESISTANCE; IDENTIFICATION; EMERGENCE;

D O I：

10.1128/AAC.00297-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Ten bla(KPC-2)-harboring Pseudomonas aeruginosa isolates from hospitals located in five different Colombian cities have been characterized. Isolates were multidrug resistant, belonged to five different pulsotypes, and possessed naturally chromosome-encoded bla(AmpC) and bla(OXA-50) genes and the acquired bla(KPC-2) gene. In most cases, the bla(KPC-2) genes were carried by plasmids of different sizes and were associated with Tn4401b or a new structure containing only part of the Tn4401 sequence. This study revealed that several clones of P. aeruginosa producing bla(KPC-2) are disseminating in Colombia.

引用

页码：5350 / 5353

页数：4

共 23 条

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