Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the Diagnosis of Multiple Sclerosis

被引:5411
作者
McDonald, WI
Compston, A
Edan, G
Goodkin, D
Hartung, HP
Lublin, FD
McFarland, HF
Paty, DW
Polman, CH
Reingold, SC
Sandberg-Wollheim, M
Sibley, W
Thompson, AJ
van den Noort, S
Weinshenker, BY
Wolinsky, JS
机构
[1] Royal Coll Physicians, London NW1 4LE, England
[2] Univ Cambridge, Cambridge, England
[3] CHU Rennes, Rennes, France
[4] Univ Calif San Francisco, San Francisco, CA 94143 USA
[5] Karl Franzens Univ Graz, Graz, Austria
[6] Mt Sinai Sch Med, New York, NY USA
[7] Natl Inst Neurol Disorders & Stroke, Bethesda, MD USA
[8] Univ British Columbia, Vancouver, BC V5Z 1M9, Canada
[9] Free Univ Amsterdam, NL-1081 HV Amsterdam, Netherlands
[10] Natl Multiple Sclerosis Soc, New York, NY USA
[11] Univ Lund Hosp, S-22185 Lund, Sweden
[12] UCL, Inst Neurol, London, England
[13] Univ Arizona, Hlth Sci Ctr, Tucson, AZ USA
[14] Neurol Inst, London, England
[15] Univ Calif Irvine, Irvine, CA USA
[16] Mayo Clin & Mayo Fdn, Rochester, MN 55905 USA
[17] Univ Texas, Hlth Sci Ctr, Houston, TX USA
关键词
D O I
10.1002/ana.1032
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The International Panel on MS Diagnosis presents revised diagnostic criteria for multiple sclerosis (MS). The focus remains on the objective demonstration of dissemination of lesions in both time and space. Magnetic resonance imaging is integrated with clinical and other paraclinical diagnostic methods. The revised criteria facilitate the diagnosis of MS in patients with a variety of presentations, including "monosymptomatic" disease suggestive of MS, disease with a typical relapsing-remitting course, and disease with insidious progression, without clear attacks and remissions. Previously used terms such as "clinically definite" and "probable MS" are no longer recommended. The outcome of a diagnostic evaluation is either MS, "possible MS" (for those at risk for MS, but for whom diagnostic evaluation is equivocal), or "not MS."
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页码:121 / 127
页数:7
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