Establishment of Four New Human Primary Cell Cultures from Chemo-Naive Italian Osteosarcoma Patients

被引：22

作者：

Laschi, Marcella ^{[1
]}

Bernardini, Giulia ^{[1
]}

Geminiani, Michela ^{[1
]}

Ghezzi, Lorenzo ^{[1
]}

Amato, Loredana ^{[1
]}

Braconi, Daniela ^{[1
]}

Millucci, Lia ^{[1
]}

Frediani, Bruno ^{[2
]}

Spreafico, Adriano ^{[3
]}

Franchi, Alessandro ^{[4
]}

Campanacci, Domenico ^{[5
]}

Capanna, Rodolfo ^{[5
]}

Santucci, Annalisa ^{[1
]}

机构：

[1] Univ Siena, Dipartimento Biotecnol Chim & Farm, I-53100 Siena, Italy

[2] Univ Siena, Policlin Le Scotte, Dipartimento Sci Med Chirurg & Neurosci, I-53100 Siena, Italy

[3] Azienda Osped Univ Senese, Policlin Le Scotte, Immunoematol Trasfus, Siena, Italy

[4] Univ Florence, Dipartimento Chirurg & Med Traslaz, Florence, Italy

[5] Azienda Osped Univ Careggi, Dipartimento Ortopedia Oncol & Chirurg Ricostrutt, Florence, Italy

来源：

JOURNAL OF CELLULAR PHYSIOLOGY | 2015年 / 230卷 / 11期

关键词：

HUMAN OSTEOBLASTIC CELLS; EZRIN EXPRESSION; RECEPTOR EXPRESSION; SRC KINASE; IN-VITRO; LINES; METASTASIS; TUMOR; D-3; DIFFERENTIATION;

D O I：

10.1002/jcp.24996

中图分类号：

Q2 [细胞生物学];

学科分类号：

071013 [干细胞生物学];

摘要：

Osteosarcoma (OS) is a primary highly malignant tumor of bone, affecting predominately adolescents and young adults between 10 and 20 years of age. OS is characterized by an extremely aggressive clinical course, with a rapid development of metastasis to the lung and distant bones. J. Cell. Physiol. 9999: 2718-2727, 2015. (c) 2015 Wiley Periodicals, Inc.

引用

页码：2718 / 2727

页数：10

共 60 条

[1]

Metabolism of vitamin D3 in human osteoblasts:: Evidence for autocrine and paracrine activities of 1α,25-dihydroxyvitamin D3 [J].

Atkins, Gerald J. ;

Anderson, Paul H. ;

Findlay, David M. ;

Welldon, Katie J. ;

Vincent, Cristina ;

Zannettino, Andrew C. W. ;

O'Loughlin, Peter D. ;

Morris, Howard A. .

BONE, 2007, 40 (06) :1517-1528

[2]

Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage [J].

Berman, Seth D. ;

Calo, Eliezer ;

Landman, Allison S. ;

Danielian, Paul S. ;

Miller, Emily S. ;

West, Julie C. ;

Fonhoue, Borel Djouedjong ;

Caron, Alicia ;

Bronson, Roderick ;

Bouxsein, Mary L. ;

Mukherjee, Siddhartha ;

Lees, Jacqueline A. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (33) :11851-11856

[3]

Proteomics of osteosarcoma [J].

Bernardini, Giulia ;

Laschi, Marcella ;

Geminiani, Michela ;

Santucci, Annalisa .

EXPERT REVIEW OF PROTEOMICS, 2014, 11 (03) :331-343

[4]

Proteomics and phosphoproteomics provide insights into the mechanism of action of a novel pyrazolo[3,4-d]pyrimidine Src inhibitor in human osteosarcoma [J].

Bernardini, Giulia ;

Laschi, Marcella ;

Serchi, Tommaso ;

Spreafico, Adriano ;

Botta, Maurizio ;

Schenone, Silvia ;

Arena, Simona ;

Geminiani, Michela ;

Scaloni, Andrea ;

Collodel, Giulia ;

Orlandini, Maurizio ;

Niccolai, Neri ;

Santucci, Annalisa .

MOLECULAR BIOSYSTEMS, 2014, 10 (06) :1305-1312

[5]

Post-genomics of bone metabolic dysfunctions and neoplasias [J].

Bernardini, Giulia ;

Braconi, Daniela ;

Spreafico, Adriano ;

Santucci, Annalisa .

PROTEOMICS, 2012, 12 (4-5) :708-721

[6]

Vitamin D and Bone [J].

Bikle, Daniel D. .

CURRENT OSTEOPOROSIS REPORTS, 2012, 10 (02) :151-159

[7]

Immunoexpression of Ezrin and CD44 in Patients With Osteosarcoma [J].

Boldrini, Erica ;

Peres, Stela Verzinhasse ;

Morini, Sandra ;

de Camargo, Beatriz .

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2010, 32 (06) :E213-E217

[8]

Bone mineralization [J].

Bonucci, Ermanno .

FRONTIERS IN BIOSCIENCE-LANDMARK, 2012, 17 :100-128

[9]

The Ezrin Metastatic Phenotype Is Associated with the Initiation of Protein Translation [J].

Briggs, Joseph W. ;

Ren, Ling ;

Nguyen, Rachel ;

Chakrabarti, Kristi ;

Cassavaugh, Jessica ;

Rahim, Said ;

Bulut, Gulay ;

Zhou, Ming ;

Veenstra, Timothy D. ;

Chen, Qingrong ;

Wei, Jun S. ;

Khan, Javed ;

Uren, Aykut ;

Khanna, Chand .

NEOPLASIA, 2012, 14 (04) :297-+

[10]

Broadhead Matthew L., 2011, Sarcoma, V2011, P959248, DOI 10.1155/2011/959248

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