Association between serotonin transporter gene polymorphism and anxiety-related traits

被引：157

作者：

Katsuragi, S

Kunugi, H

Sano, A

Tsutsumi, T

Isogawa, K

Nanko, S

Akiyoshi, J ^{[1
]}

机构：

[1] Oita Med Univ, Dept Neuropsychiat, Hasama, Oita 87955, Japan

[2] Teikyo Univ, Sch Med, Dept Neuropsychiat, Tokyo 173, Japan

[3] Ehime Univ, Sch Med, Dept Psychiat, Matsuyama, Ehime 790, Japan

来源：

BIOLOGICAL PSYCHIATRY | 1999年 / 45卷 / 03期

关键词：

serotonin; transporter; promoter; polymorphism; harm avoidance; tridimensional personality questionnaire; anxiety; personality;

D O I：

10.1016/S0006-3223(98)00090-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Background: Polymorphism in the serotonin transporter promoter gene has been recently reported to be associated with the personality trait known as anxiety-related traits. We have attempted to replicate these findings in 101 healthy Japanese subjects. Methods: The personality traits of the subjects were assessed with the tridimensional personality questionnaire. Results: An association,was observed in rite present study between individuals grouped according to the transporter gene and harm avoidance scores. Conclusions: These data supported that there was an association between the serotonin transporter gene and anxiety. Biol Psychiatry 1999:45:368-370 (C) 1999 Society of Biological Psychiatry.

引用

页码：368 / 370

页数：3