Bicyclic anti-VZV nucleosides:: Thieno analogues retain full antiviral activity

被引:19
作者
Brancale, A
McGuigan, C
Algain, B
Savy, P
Benhida, R
Fourrey, JL
Andrei, G
Snoeck, R
De Clercq, E
Balzarini, J
机构
[1] Cardiff Univ, Welsh Sch Pharm, Cardiff CF10 3XF, S Glam, Wales
[2] CNRS, Inst Chim Subst Nat, F-91198 Gif Sur Yvette, France
[3] Katholieke Univ Leuven, Rega Inst Med Res, B-3000 Louvain, Belgium
关键词
D O I
10.1016/S0960-894X(01)00471-1
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Thieno analogues of the potent and selective furo-pyrimidine anti-VZV nucleoside family are herein reported. The compounds retain full antiviral potency in comparison to the furo parent. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:2507 / 2510
页数:4
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