Elliagic acid, pomegranate and prostate cancer - a mini review

被引：114

作者：

Bell, Carolyn ^{[1
]}

Hawthorne, Susan ^{[1
]}

机构：

[1] Queens Univ Belfast, Ctr Med Biol, Sch Pharm, Belfast BT9 7BL, Antrim, North Ireland

来源：

JOURNAL OF PHARMACY AND PHARMACOLOGY | 2008年 / 60卷 / 02期

关键词：

D O I：

10.1211/jpp.60.2.0001

中图分类号：

R9 [药学];

学科分类号：

1007 [药学];

摘要：

There is currently a shifting focus towards finding natural compounds that may prevent or treat cancer, due to the problems that exist with current chemotherapeutic regimens. The fruit of the Punica granatum (pomegranate) contains hundreds of phytochemicals and pomegranate extracts have recently been shown to exhibit antioxidant properties, thought to be due to the action of ellagic acid, the main polyphenol in pomegranate. In this mini review the effects of pomegranate extracts and ellagic acid on the proliferation of prostate cancer cells and their future potential are discussed.

引用

页码：139 / 144

页数：6

共 57 条

[1]

Combined inhibitory effects of green tea polyphenols and selective cyclooxygenase-2 inhibitors on the growth of human prostate cancer cells both in vitro and in vivo [J].

Adhami, Vaqar Mustafa ;

Malik, Arshi ;

Zaman, Najia ;

Sarfaraz, Sami ;

Siddiqui, Imtiaz Ahmad ;

Syed, Deeba Nadeem ;

Afaq, Farrukh ;

Pasha, Farrukh Sierre ;

Saleem, Mohammad ;

Mukhtar, Hasan .

CLINICAL CANCER RESEARCH, 2007, 13 (05) :1611-1619

[2]

Molecular targets of dietary agents for prevention and therapy of cancer [J].

Aggarwal, BB ;

Shishodia, S .

BIOCHEMICAL PHARMACOLOGY, 2006, 71 (10) :1397-1421

[3]

Pomegranate extracts potently suppress proliferation, xenograft growth, and invasion of human prostate cancer cells [J].

Albrecht, M ;

Jiang, WG ;

Kumi-Diaka, J ;

Lansky, EP ;

Gommersall, LM ;

Patel, A ;

Mansel, RE ;

Neeman, I ;

Geldof, AA ;

Campbell, MJ .

JOURNAL OF MEDICINAL FOOD, 2004, 7 (03) :274-283

[4]

[Anonymous], PATHOLOGY PROSTATE

[5]

Clinical trials of natural products as chemopreventive agents for prostate cancer [J].

Bemis, Debra L. ;

Katz, Aaron E. ;

Buttyan, Ralph .

EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2006, 15 (10) :1191-1200

[6]

Predisposing gene for early-onset prostate cancer, localized on chromosome 1q42.2-43 [J].

Berthon, P ;

Valeri, A ;

Cohen-Akenine, A ;

Drelon, E ;

Paiss, T ;

Wöhr, G ;

Latil, A ;

Millasseau, P ;

Mellah, I ;

Cohen, N ;

Blanché, H ;

Bellané-Chantelot, C ;

Demenais, F ;

Teillac, P ;

Le Duc, A ;

de Petriconi, R ;

Hautmann, R ;

Chumakov, I ;

Bachner, L ;

Maitland, NJ ;

Lidereau, R ;

Vogel, W ;

Fournier, G ;

Mangin, P ;

Cohen, D ;

Cussenot, O .

AMERICAN JOURNAL OF HUMAN GENETICS, 1998, 62 (06) :1416-1424

[7]

Chemoprevention of human prostate cancer by oral administration of green tea catechins in volunteers with high-grade prostate intraepithelial neoplasia: A preliminary report from a one-year proof-of-principle study [J].

Bettuzzi, S ;

Brausi, M ;

Rizzi, F ;

Castagnetti, G ;

Peracchia, G ;

Corti, A .

CANCER RESEARCH, 2006, 66 (02) :1234-1240

[8]

BUSBY JE, 2006, J UROLOGY, V176, P1714

[9]

Castonguay A, 1997, INT J ONCOL, V10, P367

[10]

What causes prostate cancer? A brief summary of the epidemiology [J].

Chan, JM ;

Stampfer, MJ ;

Giovannucci, EL .

SEMINARS IN CANCER BIOLOGY, 1998, 8 (04) :263-273

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